免疫炎症因素在烟雾病发病中的研究进展  

Research progress on immune inflammatory factors in the pathogenesis of moyamoya disease

作　　者：林峰 陈典达 肖金林 武续业 曾而明[1] LIN Feng;CHEN Dianda;XIAO Jinlin(Department of Neurosurgery,The First Affiliated Hospital of Nanchang University,Nanchang 330006,China)

机构地区：[1]南昌大学第一附属医院神经外科,南昌330006

出　　处：《临床神经外科杂志》2023年第4期466-469,共4页Journal of Clinical Neurosurgery

基　　金：江西省自然科学基金资助项目(20192BAB205046);江西省重点研发计划项目(20202BBG73030)。

摘　　要：烟雾病(MMD)是一种慢性进展性闭塞性脑血管病,其发病机制目前尚不明确。越来越多的证据表明,免疫炎症因素参与了MMD的发生发展。免疫相关性基因、炎症标记物、免疫细胞等在MMD中表达异常。本文对近年来免疫炎症在MMD发病中的相关研究进展进行综述。Moyamoya disease(MMD)is a chronic progressive occlusive cerebrovascular disease,the pathogenesis of which is still unclear.There is growing evidence that immunoinflammatory factors are involved in the development of MMD.Immune-related genes,inflammatory markers,and immune cells are expressed aberrantly in MMD.This paper reviews the recently progressed research on immune inflammation in the pathogenesis of MMD.

关 键 词：烟雾病 免疫 炎症 发病机制 

分 类 号：R743[医药卫生—神经病学与精神病学] R651[医药卫生—临床医学]