智能假肢的人机接口构建技术——靶向肌肉神经功能重建  

Targeted muscle reinnervation:a surgical technique of human-machine interface for intelligent prosthesis

作　　者：郭耀 赵巍 黄剑平[2] 申明奎 李思敬 刘诚 苏秀云 李光林[2] 毕胜 裴国献 GUO Yao;ZHAO Wei;HUANG Jianping;SHEN Mingkui;LI Sijing;LIU Cheng;SU Xiuyun;LI Guanglin;BI Sheng;PEI Guoxian(Medical College of Southern University of Science and Technology,Shenzhen Guangdong,518055,P.R.China;Shenzhen Institute of Advanced Technology,Chinese Academy of Sciences,Shenzhen Guangdong,518055,P.R.China;Department of Orthopedics,Southern University of Science and Technology Hospital,Shenzhen Guangdong,518055,P.R.China;National Research Center for Rehabilitation Technical Aids,Beijing,100176,P.R.China)

机构地区：[1]南方科技大学医学院,广东深圳518055 [2]中国科学院深圳先进技术研究院,广东深圳518055 [3]南方科技大学医院骨科,广东深圳518055 [4]国家康复辅具研究中心,北京100176

出　　处：《中国修复重建外科杂志》2023年第8期1021-1025,共5页Chinese Journal of Reparative and Reconstructive Surgery

基　　金：国家重点研发计划“变革性技术关键科学问题”重点专项(2017YFA0701100);南方科技大学科研启动学校配套经费(Y01416214);深港联合资助项目(SGDX20211123114204007);中国博士后科学基金第73批面上资助(2023M731522)。

摘　　要：目的综述用于构建智能假肢人机接口的靶向肌肉神经功能重建(targeted muscle reinnervation,TMR)手术,为截肢患者的残肢功能重建提供新的临床干预范式。方法广泛查阅国内外相关文献,系统性阐述智能假肢的外科需求、TMR手术方案、目标人群与预后,以及TMR的发展与未来。结果TMR手术通过重建“大脑-脊髓-外周神经-骨骼肌”的神经传导通路,增加模式识别所需的表面肌电信号,促进截肢患者对于智能假肢的直觉操控。TMR术前应根据截肢患者的残肢情况及功能需求设计个性化手术方案,不同目的的TMR手术应针对不同目标人群。结论TMR手术已被国外认证为改善假肢操控能力的变革性技术,有望成为国内200万截肢患者新的临床干预范式。Objective To review targeted muscle reinnervation(TMR)surgery for the construction of intelligent prosthetic human-machine interface,thus providing a new clinical intervention paradigm for the functional reconstruction of residual limbs in amputees.Methods Extensively consulted relevant literature domestically and abroad and systematically expounded the surgical requirements of intelligent prosthetics,TMR operation plan,target population,prognosis,as well as the development and future of TMR.Results TMR facilitates intuitive control of intelligent prostheses in amputees by reconstructing the“brain-spinal cord-peripheral nerve-skeletal muscle”neurotransmission pathway and increasing the surface electromyographic signals required for pattern recognition.TMR surgery for different purposes is suitable for different target populations.Conclusion TMR surgery has been certified abroad as a transformative technology for improving prosthetic manipulation,and is expected to become a new clinical paradigm for 2 million amputees in China.

关 键 词：智能假肢 人机接口 模式识别 表面肌电信号 靶向肌肉神经功能重建 

分 类 号：R318.1[医药卫生—生物医学工程]