广西百色市3~5岁儿童白色念珠菌检出及患龋情况影响因素研究  

Study on the factors influencing the detection of Candida albicans and dental caries in children aged 3-5 years in Baise City,Guangxi

作　　者：蒋依玲 莫丹 张艺山 邓思成 高琬珊 邱荣敏[1] JIANG Yi-ling;MO Dan;ZHANG Yi-shan;DENG Si-cheng;GAO Wan-shan;QIU Rong-min(Department of Pediatric Dentistry,College of Stomatology,Hospital of Stomatology,Guangxi Medical University&Guangxi Key Laboratory of Oral and Maxillofacial Rehabilitation and Reconstruction&Guangxi Clinical Research Center for Craniofacial Deformity&Guangxi Key Laboratory of Oral and Maxillofacial Surgery Disease Treatment&Guangxi Health Commission Key Laboratory of Prevention and Treatment for Oral Infectious Diseases,Nanning 530021,China)

机构地区：[1]广西医科大学口腔医学院·附属口腔医院儿童口腔科,广西口腔颌面修复与重建研究自治区级重点实验室,广西颅颌面畸形临床医学研究中心,广西口腔颌面修复与重建研究重点实验室,广西壮族自治区卫生健康委员会口腔感染性疾病防治重点实验室,广西南宁530021

出　　处：《中国实用口腔科杂志》2023年第4期452-456,461,共6页Chinese Journal of Practical Stomatology

基　　金：广西医科大学青年科学基金资助(GXMUYSF:201320)。

摘　　要：目的探讨广西百色市3~5岁儿童白色念珠菌检出及患龋情况的影响因素。方法于2016年9月至2017年12月随机选取广西百色市3~5岁的392名儿童行口腔检查及问卷调查;收集儿童牙菌斑样本,培养并鉴定白色念珠菌;统计并分析影响牙菌斑中白色念珠菌检出情况及患龋情况的相关因素。结果牙菌斑中有白色念珠菌检出儿童137名,检出率为34.9%(137/392);患龋儿童为284名,患龋率为72.4%(284/392),龋均为4.75±4.92。对牙菌斑中白色念珠菌检出情况相关影响因素的分析结果显示,仅睡前是否吃甜食的差异有统计学意义(P=0.010),且为牙菌斑中白色念珠菌检出的独立危险因素(OR=1.731,95%CI:1.136~2.637,P=0.011);对患龋情况相关影响因素的分析结果显示,睡前是否吃甜食及牙菌斑中是否有白色念珠菌检出的差异有统计学意义(均P<0.05),且牙菌斑中白色念珠菌检出情况是患龋的独立危险因素(OR=3.406,95%CI:1.935~5.998,P<0.001)。结论睡前吃甜食的习惯可能会促进白色念珠菌在广西百色市3~5岁儿童的牙面定植,进而增加患龋风险。Objective To investigate the factors influencing the detection of Candida albicans and caries in children aged 3-5 years in Baise City,Guangxi.Methods Totally 392 children aged 3-5 years in Baise City,Guangxi were selected by whole group sampling and random sampling methods,and oral examination and questionnaire survey were conducted;dental plaque samples were collected,and Candida albicans was cultured and identified;the related factors affecting the detection of Candida albicans and caries were counted and analyzed.Results The number of children detected with Candida albicans in dental plaque was 137,and the detection rate was 34.9%(137/392);the number of children with dental caries was284,the prevalence caries was 72.4%(284/392),and the mean dmft was 4.75±4.92;concerning the related factors in the presence or absence of Candida albicans in dental plaque,only the difference of whether or not to eat sweets before bedtime was statistically significant(P=0.010),and was an independent risk factor for the detection of Candida albicans in dental plaque(OR=1.731,95%CI:1.136-2.637,P=0.011);concerning the relevant factors in the presence or absence of dental caries,only the difference of whether or not to eat sweets before bedtime and whether or not Candida albicans being detected in dental plaque had statistical significance(P 0.05),and the detection of Candida albicans in dental plaque was an independent risk factor for the risk of dental caries(OR=3.406,95%CI:1.935-5.998,P 0.001).Conclusion The habit of eating sweets at bedtime may promote Candida albicans to colonize the teeth of children aged 3-5 in Baise,Guangxi,which in turn increases the risk of early childhood caries.

关 键 词：白色念珠菌 低龄儿童龋 甜食 

分 类 号：R78[医药卫生—口腔医学]