离焦环大小及其与瞳孔直径的关系对近视患者配戴角膜塑形镜后眼轴增长的影响  

Effect of peripheral plus ring diameter and its relationship with pupil diameter on axial elongation in myopic patients after wearing orthokeratology lenses

作　　者：于嘉 张晶 周跃华 袁晓辉 周其亮 李辰 Yu Jia;Zhang Jing;Zhou Yuehua;Yuan Xiaohui;Zhou Qiliang;Li Chen(Eye School,Chengdu University of Traditional Chinese Medicine,Ineye Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China;Beijing Ming Vision and Ophthalmology,Beijing 100062,China)

机构地区：[1]成都中医药大学眼科学院,成都中医大银海眼科医院,成都610075 [2]北京茗视光眼科,北京100062

出　　处：《中华实验眼科杂志》2023年第8期776-781,共6页Chinese Journal Of Experimental Ophthalmology

摘　　要：目的探讨近视患者配戴角膜塑形镜后离焦环大小及其与瞳孔直径(PD)的关系是否会影响眼轴长度(AL)增长速度。方法采用病例对照研究方法,纳入2020年1—6月在北京茗视光眼科配戴角膜塑形镜的近视患者100例100眼,分别于戴镜前及戴镜后3、6、9和12个月采用光学生物测量仪测量眼轴长度(AL)和中央角膜厚度(CCT),采用角膜地形图仪测量角膜陡峭曲率(Ks)和角膜平坦曲率(Kf)。根据配戴角膜塑形镜后1年角膜地形图差异图模式上离焦环直径(PPRD)与PD关系,将研究对象分为较大PPRD(LPPRD)组(PD0.05)。2个组患者戴镜前后不同时间点PD总体比较,差异均无统计学意义(F分组=1.133,P=0.293;F时间=231.427,P=0.112)。结论离焦环大小及其与PD的关系是影响角膜塑形镜配戴后近视患者AL增长速度的主要原因之一,PPRD更小者AL增长更缓慢,近视控制效果更好。Objective To investigate the effect of peripheral plus ring size and its potential associations with pupil diameter(PD)on axial length(AL)elongation in myopic patients after wearing orthokeratology lenses.Methods A case-control study was conducted.One hundred eyes from 100 myopic patients who underwent orthokeratolokgy lenses fitting were enrolled at Beijing Ming Vision and Ophthalmology from January to June 2020.AL and central corneal thickness(CCT)measurements were obtained using Lenstar LS900 ocular biometry,and steep keratometry(Ks),flat keratometry(Kf)were assessed using the TMS-4 corneal topographer.The patients were divided into larger peripheral plus ring diameter(LPPRD)group consisting of 55 eyes with PD<PPRD-0.9 mm and smaller PPRD(SPPRD)group consisting of 45 eyes with PPRD-0.9 mm<PD<PPRD+0.9 mm based on PPRD and PD sizes in the tangential difference map.Differences in the above parameters before and after wearing orthokeratology lenses were compared between the two groups.The study followed the Declaration of Helsinki.The study protocol was approved by the Ethics Committee of Ineye Hospital of Chengdu University of Traditional Chinese Medicine(No.2021yh-008).All the subjects and their guardians understood the purpose and method of the study and signed the informed consent voluntarily.Results The PPRD of LPPRD group was(5.15±0.37)mm 12 months after wearing orthokeratology lenses,which was significantly higher than(4.75±0.32)mm of SPPRD group(t=0.214,P<0.01).The elongation of AL at 3,6,9 and 12 months after wearing orthokeratology lenses were(0.13±0.07),(0.23±0.11),(0.31±0.13)and(0.36±0.41)mm in LPPRD group,and(0.06±0.05),(0.11±0.06),(0.14±0.07)and(0.17±0.08)mm in SPPRD group,respectively.There were significant differences in AL elongation at different time points after wearing orthokeratology lenses between the two groups(F group=30.527,P<0.01;F time=16.528,P<0.01),and the AL elongation at different time points was smaller in SPPRD group than in LPPRD group,showing statistically significant d

关 键 词：近视 治疗 角膜塑形术 离焦环 眼轴长度 近视性离焦 

分 类 号：R778.11[医药卫生—眼科]