鱼类神经行为毒性研究进展  

Fish as A Potential Model System for Neurobehavioral Toxicity

作　　者：王旭 闫有利 WANG Xu;YAN Youli(Freshwater Fisheries Science Institute of Liaoning Province,Key Laboratory for Prevention and Treatment of Aquatic Animal Diseases of Liaoning Province,Liaoyang,Liaoning 111000,China)

机构地区：[1]辽宁省淡水水产科学研究院,辽宁省水生动物病害防治重点实验室,辽宁辽阳111000

出　　处：《水产养殖》2023年第8期42-48,共7页Journal of Aquaculture

基　　金：国家现代农业产业技术体系资助(CARS-45)。

摘　　要：从鱼类生物学特征、试验鱼类、鱼类全基因组测序和鱼类种内变异(品系、年龄、性别、个体差异和社会地位)4个方面,简述了鱼类神经行为毒性研究进展。指出,鱼类是开展神经行为毒性研究的重要物种。提出,应注重受试试验鱼类的多样性;建立鱼类神经行为毒性数据库;解析鱼类神经行为毒性分子机制。The article reviews recent research progress on neurobehavioral toxicology studies using fish:biological characteristics,strains and whole genome sequencing,and intraspecies variation(laboratory fish strains,age,sex,individual differences and social status).And fish is as a particularly and promisingly useful model organism in neurobehavioral toxicity.Future research directions are proposed to lay emphasis on species diversity of tested fish,establish a database of neurobehavioral toxicology studies in fish and analyze the molecular mechanisms of neurobehavioral toxicology in fish.

关 键 词：鱼类 生物学特征 试验鱼类品系 全基因组测序 种内变异 神经行为毒性 

分 类 号：S917.4[农业科学—水产科学]