食管癌患者术后发生急性呼吸衰竭的影响因素研究  

Study on the Influencing Factors of Postoperative Acute Respiratory Failure in Patients with Esophageal Cancer

作　　者：刘会鹏[1] 李莉[2] 张彦平[1] LIU Huipeng;LI Li;ZHANG Yanping(The Second Affiliated Hospital of Zhengzhou University,Zhengzhou,450000)

机构地区：[1]郑州大学第二附属医院,450000 [2]郑州大学第一附属医院,450000

出　　处：《实用癌症杂志》2023年第9期1536-1539,共4页The Practical Journal of Cancer

摘　　要：目的探究食管癌患者术后发生急性呼吸衰竭的相关危险因素,为临床防治提供参考。方法回顾性分析124例食管癌患者临床资料,依据术后是否发生急性呼吸衰竭分为研究组(18例)及对照组(106例)。收集2组一般资料,开展Logistic回归分析影响术后发生急性呼吸衰竭的相关因素。结果多因素分析显示,年龄、吸烟指数、术前肺功能、术前合并症、手术时间、术中晶体液输入量、术后并发症是食管癌患者术后发生急性呼吸衰竭的独立影响因素(P<0.05且OR>1)。结论年龄≥60岁患者、吸烟史较长、术前肺功能损伤严重、合并严重的基础性疾病、手术时间>3 h、大量输入晶体液、术后并发症等是导致食管癌患者术后发生呼吸衰竭的独立危险因素,在临床干预中需注意围术期内年龄≥60岁的患者情况,必要时可于术前改善肺功能、控制晶体液输入量、缩短手术时间,以降低术后并发症发生率,从而预防术后急性呼吸衰竭。Objective To explore the related risk factors of postoperative acute respiratory failure in patients with esophageal cancer,and to provide reference for clinical prevention and treatment.Methods The clinical data of 124 patients with esophageal cancer were retrospectively analyzed,and they were divided into the study group(18 cases)and the control group(106 cases)based on whether acute respiratory failure occurred after surgery.Collect 2 groups of general data and conduct logistic regression analysis on the relevant factors affecting the occurrence of acute respiratory failure after surgery.Results Multivariate analysis showed that age,smoking index,preoperative pulmonary function,preoperative complications,surgical time,intraoperative lens fluid input,and postoperative complications were independent influencing factors for postoperative acute respiratory failure in patients with esophageal cancer(P<0.05 and OR>1).Conclusion Patients with age≥60 years old,a long history of smoking,severe preoperative lung function damage,severe underlying diseases,surgery time>3 hours,large amounts of crystalloid fluid infusion,and postoperative complications are independent risk factors for postoperative respiratory failure in patients with esophageal cancer.In clinical intervention,attention should be paid to the situation of patients with age≥60 years old during the perioperative period,and if necessary,preoperative improvement of lung function,control of crystalloid fluid infusion Shorten the operation time to reduce the incidence of postoperative complications,thereby preventing postoperative acute respiratory failure.

关 键 词：食管癌 急性呼吸衰竭 因素分析 并发症 

分 类 号：R735.1[医药卫生—肿瘤]