甲状腺全切除术治疗甲状腺癌的临床效果及对甲状旁腺激素水平的影响  

Clinical effect of total thyroidectomy for thyroid cancer and its influence on parathyroid hormone level

作　　者：毛英[1] MAO Ying(Hospital of People's Liberation Army,Yingtan,Jiangxi,335000,China)

机构地区：[1]中国人民解放军联勤保障部队第九〇八医院,江西鹰潭335000

出　　处：《当代医学》2023年第8期122-125,共4页Contemporary Medicine

摘　　要：目的探讨甲状腺全切除术治疗甲状腺癌的临床疗效及对甲状旁腺激素水平的影响。方法选取2019年6月至2020年12月本院收治的100例甲状腺癌患者作为研究对象,随机分为对照组与实验组,每组50例。对照组采用甲状腺次全切除术,实验组采用甲状腺全切除术,比较两组临床疗效、治疗前后甲状旁腺激素水平、并发症发生率及术后6个月生存率。结果实验组治疗总有效率高于对照组,差异有统计学意义(P<0.05)。治疗前,两组甲状旁腺素水平比较差异无统计学意义;治疗后,两组甲状旁腺素水平均低于治疗前,且实验组低于对照组,差异有统计学意义(P<0.05)。实验组并发症总发生率高于对照组,术后6个月生存率高于对照组,差异均有统计学意义(P<0.05)。结论甲状腺全切除术治疗甲状腺癌患者效果显著,可明显提高患者术后生存率,但易导致患者术后甲状旁腺激素水平降低,增加术后并发症的发生,临床需根据患者实际情况慎重选择。Objective To explore the clinical effect of total thyroidectomy for thyroid cancer and its influence on parathyroid hormone level.Methods A total of 100 patients with thyroid cancer admitted to our hospital from June 2019 to December 2020 were selected as research subjects,and they were randomly divided into control group and experimental group,with 50 cases in each group.Subtotal thyroidectomy was performed in the control group,while total thyroidectomy was performed in the experimental group,the clinical efficacy,parathyroid hormone levels before and after treatment,incidence of complications and survival rate 6 months postoperative were compared between the two groups.Results The total effective rate in the experimental group was higher than that in the control group,the difference was statistically significant(P<0.05).Before treatment,There was no significant difference in parathyroid hormone levels between the two groups;after treatment,the parathyroid hormone levels in the two groups were lower than those before treatment,and the experimental group was lower than that in the control group,the difference was statistically significant(P<0.05).The total complication rate in the experimental group was higher than that in the control group,and the 6 months postoperative survival rate was higher than that inthe reference group,the difference was statistically significant(P<0.05).Conclusion Total thyroidectomy has a remarkable effect in the treatment of thyroid cancer patients,which can significantly improve the postoperative survival rate of patients,it is easy to reduce the level of postoperative parathyroid hormone in patients and increase the occurrence of postoperative complications,therefore,careful selection should be made according to the actual situation of patients in clinical practice.

关 键 词：甲状腺癌 甲状腺全切除术 治疗效果 甲状旁腺激素水平 并发症 生存率 

分 类 号：R736.1[医药卫生—肿瘤]