根尖刮治术与根尖切除术治疗复杂慢性根尖周炎的临床疗效及对患者炎症指标的影响  

Clinical efficacy of apical curettage and apicectomy in the treatment of complex chronic periapical inflammation and its influence on inflammatory indexes

作　　者：蓝丁梅 李志雄[1] 胡河添 彭运香 宋利容 LAN Dingmei;LI Zhixiong;HU Hetian;PENG Yunxiang;SONG Lirong(Department of Stomatology,Wuhua County People's Hospital,Meizhou,Guangdong,514400,China)

机构地区：[1]五华县人民医院口腔科,广东梅州514400

出　　处：《当代医学》2023年第4期50-53,共4页Contemporary Medicine

摘　　要：目的探讨根尖刮治术与根尖切除术治疗复杂慢性根尖周炎的临床疗效及对患者炎症指标的影响。方法选取2018年6月至2021年6月本院收治的70例复杂慢性根尖周炎患者作为研究对象,根据治疗方式不同分为刮治组与切除组,各35例。刮治组采用根尖刮治术治疗,切除组采用根尖切除术治疗,比较两组临床疗效、术后疼痛程度、炎症指标[肿瘤坏死因子(TNF)-α、白细胞介素(IL)-1、IL-6]水平及术后并发症发生情况。结果切除组治疗总有效率为97.14%,高于刮治组的82.86%,差异有统计学意义(P<0.05)。两组视觉模拟评分法(VAS)评分时间、交互比较差异有统计学意义(P<0.05);两组组间不同时间点视觉模拟评分法(VAS)比较差异无统计学意义;两组术后各时间点VAS评分均低于前一时点,差异有统计学意义(P<0.05)。术后1个月,切除组TNF-α、IL-1、IL-6水平均低于刮治组,差异有统计学意义(P<0.05)。切除组术后并发症发生率为5.71%,低于刮治组的22.86%,差异有统计学意义(P<0.05)。结论与根尖刮治术相比,根尖切除术治疗复杂慢性根尖周炎的临床疗效更显著,可明显降低患者术后炎症指标及并发症发生率,安全性较高,值得临床推广应用。Objective To investigate the clinical efficacy of apical curettage and apicectomy in the treatment of complex chronic periapical in-flammation and its influence on inflammatory indexes.Methods A total of 70 patients with complex chronic periapical periodontitis admitted to our hospital from June 2018 to June 2021 were selected as the research subjects,and they were divided into the curettage group and the resection group according to different treatment methods,with 35 cases in each group.The curettage group was treated with apical curettage,and the resection group was treated with apical resection,the clinical efficacy,postoperative pain,levels of inflammatory indicators(tumor necrosis factor[TNF-α],interleu-kin[IL]-1,IL-6)and incidence of postoperative complications were compared between the two groups.Results The total effective rate in the resec-tion group was 97.14%,which was higher than 82.86%in the curettage group,the difference was statistically significant(P<0.05).There were statis-tically significant differences in visual analogue scale(VAS)score time and interaction between the two groups(P<0.05);there was no significant difference in VAS scores at different time points between the two groups;VAS scores of the two groups at each time point after surgery were lower than those at the previous time point,and the difference was statistically significant(P<0.05).1 month after surgery,the levels of TNF-α,IL-1 and IL-6 in the resection group were lower than those in the curettage group,the difference was statistically significant(P<0.05).The total incidence of postoperative complications in the resection group was 5.71%,which was lower than 22.86%in the curettage group,and the difference was statisti-cally significant(P<0.05).Conclusion Compared with apical curettage,apical resection has more significant clinical efficacy in the treatment of complex chronic apical periapical inflammation,which can significantly reduce postoperative inflammatory indicators and the incidence of complica-tions,and has high saf

关 键 词：根尖刮治术 根尖切除术 慢性根尖周炎 临床疗效 炎症指标 

分 类 号：R781.341[医药卫生—口腔医学]