北京市朝阳区城乡居民结直肠癌癌前期病变筛查的检出情况及其影响因素  

Detection and influencing factors of precancerous lesions in colorectal cancer screening among urban and rural residents in Chaoyang district,Beijing

作　　者：刘伟 彭彦 LIUWei;PENG Yan(Department of Medicine,Beijing Chaoyang Sanhuan Cancer Hospital,Beijing,100122,China)

机构地区：[1]北京市朝阳区三环肿瘤医院内科,北京100122

出　　处：《当代医学》2023年第4期57-60,共4页Contemporary Medicine

摘　　要：目的分析北京市朝阳区城乡居民结直肠癌癌前病变筛查的检出情况及其影响因素。方法选取2021年1月至2022年3月北京市朝阳区内6613名城乡居民作为研究对象,均进行大便潜血试验、电子结肠镜检查及基本信息问卷调查。统计结直肠癌癌前病变检出情况,采用单因素及多因素Logistic回归分析结直肠癌前病变的危险因素。结果6613名受检者中,检出结直肠癌癌前病变1100例,非结直肠癌癌前病变5513名。结直肠癌癌前病变患者与非结直肠癌癌前病变患者体重指数(BMI)、工作类型、既往消化道病史、家族遗传病史、吸烟史、饮酒史、饮食习惯比较差异有统计学意义(P<0.05);多因素Logistic回归分析结果显示,脑力工作、有消化道病史、有家族遗传病史、有吸烟史、有饮酒史和低纤维、高热量、高脂肪饮食习惯是引起结直肠癌病变的危险因素(OR>1,P<0.05)。结论脑力工作、有消化道病史、有家族遗传病史、有吸烟史、有饮酒史和低纤维、高热量、高脂肪饮食习惯是引起结直肠癌病变的危险因素,因此,早期筛查、早期发现癌前病变、早期干预十分重要。Objective To analyze the detection rate of precancerous lesions of colorectal cancer and its influencing factors among urban and rural residents in Chaoyang district of Beijing.Methods 6613 urban and rural residents in Chaoyang district of Beijing from January 2021 to March 2022 were selected as the research subjects,all of them underwent stool occult blood test,electronic colonoscopy and basic information questionnaire survey.The detection of precancerous lesions of colorectal cancer was statistically analyzed,and the risk factors of colorectal precancerous lesions were analyzed by univariate and Logistic regression.Results Among the 6613 subjects examined,1100 cases of colorectal cancer precancerous lesions,and the 5513 cases of non-colorectal cancer precancerous lesions.There were statistically significant differences in body mass index(BMI),work type,previous gastrointestinal history,family genetic history,smoking history,drinking history,eating habits between the paitents with colorectal cancer precancerous lesions and non-colorectal cancer precancerous lesions(P<0.05).Multivariate Logistic regression analysis showed that mental work,history of digestive tract disease,family history of genetic disease,smoking history,drinking history and low-fiber,high-calorie,high-fat diet habits were risk factors for colorectal cancer(OR>1,P<0.05).Conclusion Mental work,history of digestive tract disease,family history of genetic disease,smoking history,drinking history and low-fiber,high-calorie,high-fat diet habits were risk factors for colorectal cancer.Therefore,early screening,early detection of precancerous lesions,and early intervention are very important.

关 键 词：结直肠癌前病变 早期筛查 检出情况 影响分析2022 

分 类 号：R735.37[医药卫生—肿瘤] R730.44[医药卫生—临床医学]