颈动脉粥样硬化斑块特征与脑小血管病影像特征的相关性研究  

Correlations between Carotid Atherosclerotic Plaque Characteristics and Cerebral Small Vessel Diseases Imaging Characteristics

作　　者：刘颖[1] 霍然 徐慧敏[1] 王筝[1] 王涛[2] 袁慧书[1] LIU Ying;HUO Ran;XU Huimin(Department of Radiology,Peking University Third Hospital,Beijing 100191,P.R.China)

机构地区：[1]北京大学第三医院放射科,100191 [2]北京大学第三医院神经外科,100191

出　　处：《临床放射学杂志》2023年第7期1071-1075,共5页Journal of Clinical Radiology

摘　　要：目的分析颈动脉中-重度狭窄患者斑块特征与脑小血管病影像征象之间相关性。方法采用MR血管壁成像分析75例颈动脉中-重度狭窄患者斑块特征,探讨与腔隙性脑梗死(腔梗)和微出血灶(CMBs)的相关性。结果有无腔隙性脑梗死时,标准化管壁指数(NWI)和斑块内出血(IPH)最大面积百分比差异存在统计学意义。有无微出血灶时,斑块负荷及斑块成分差异均无统计学意义。微出血灶个数与斑块负荷、斑块成分未见明显相关。结论颈动脉中-重度狭窄时,NWI和斑块成分中IPH增加,可能影响脑血流灌注,形成脑小血管病影像学特征。Objective To analyze the correlation between the plaque characteristics and cerebral small vessel disease imaging characteristics in patients with moderate to severe carotid stenosis.Methods The plaque characteristics of 75 patients with carotid artery moderate to severe stenosis were analyzed by MR wall imaging.The correlations between lacunar infarction,cerebral microbleeds(CMBs)and plaque characteristics were analyzed.Results There were significant differences of normalized wall index(NWI)and the maximum area percentage of intraplaque hemorrhage(IPH)in plaque with or without lacunar cerebral infarction.There were no significant differences of patients in plaque load and plaque components.There were no correlations between plaque load,plaque components and the number of CMBs.Conclusion The increase of NWI and plaque IPH may affect cerebral blood flow perfusion and form related manifestations of cerebral small vessel disease.

关 键 词：颈动脉粥样硬化斑块 血管壁成像 腔隙性脑梗死 微出血 斑块内出血 

分 类 号：R743.3[医药卫生—神经病学与精神病学]