喉部分切除术联合术后放疗对喉癌患者的影响  

Effect of Partial Laryngectomy Combined with Postoperative Radiotherapy in Patients with Laryngeal Cancer

作　　者：唐强 Tang Qiang(The Affiliated Cancer Hospital of Guizhou Medical University,Guiyang 550000,Guizhou Province,China)

机构地区：[1]贵州医科大学附属肿瘤医院,贵州贵阳550000

出　　处：《中国社区医师》2023年第23期29-31,共3页Chinese Community Doctors

摘　　要：目的:分析对喉癌患者实施喉部分切除术联合术后放疗对患者炎性因子、术后并发症发生率、生活质量的影响。方法:选取2020年2月—2023年2月贵州医科大学附属肿瘤医院收治的51例喉癌患者作为研究对象,采用电脑随机分组法分为两组。对照组采用喉部分切除术治疗,观察组在对照组基础上实施术后放疗干预。对比两组炎性因子水平、术后并发症发生情况及复发情况、生活质量。结果:治疗前,两组白细胞介素-2(IL-2)、白细胞介素-6(IL-6)、C反应蛋白(CRP)水平比较,差异无统计学意义(P>0.05);治疗后,观察组IL-2水平高于对照组,IL-6、CRP水平低于对照组,差异有统计学意义(P<0.05)。观察组术后并发症总发生率及复发率低于对照组,差异有统计学意义(P<0.05)。治疗前,两组社会职能、心理功能、生理功能评分及总分比较,差异无统计学意义(P>0.05);治疗后,两组社会职能、心理功能、生理功能评分及总分均高于治疗前,且观察组高于对照组,差异有统计学意义(P<0.05)。结论:喉癌患者采用喉部分切除术联合术后放疗,可改善患者预后,减轻炎性反应,提高患者术后生活质量水平,降低术后并发症发生率及复发率。Objective:To analyze the effect of partial laryngectomy combined with postoperative radiotherapy on the inflammatory factions,the incidence of postoperative complications and quality of life of patients with laryngeal cancer.Methods:Fifty-one patients with laryngeal cancer admitted to the Affiliated Cancer Hospital of Guizhou Medical University from February 2020 to February 2023 were selected as the study subjects.These patients were divided into two groups by computer random grouping method.The control group was treated with partial laryngectomy and the observation group were treated with postoperative radiotherapy intervention on the basis of control group.The levels of inflammatory factors,the occurrence of postoperative complications and recurrence,and quality of life were compared between the two groups.Results:Before treatment,there was no statistically significant difference in the levels of interleukin-2(IL-2),interleukin-6(IL-6)and C-reactive protein(CRP)between the two groups(P>0.05).After treatment,the IL-2 levels in the observation group were higher than those in the control group,and the levels of IL-6 and CRP in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).The total incidence of postoperative complications and recurrence rate in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05).Before treatment,there were no significant differences in the scores of social function,psychological function,physiological function and total scores between the two groups(P>0.05).After treatment,the scores of social function,psychological function,physiological function and physiological function and total scores in the two groups were higher than those before treatment,and the observation group was higher than the control group,and the difference was statistically significant(P<0.05).Conclusion:Partial laryngectomy combined with postoperative radiotherapy can improve the pro

关 键 词：喉癌 喉部分切除术 放疗 生活质量 并发症 

分 类 号：R739.65[医药卫生—肿瘤]