以干咳为唯一症状的原发性肺黏膜相关淋巴组织淋巴瘤1例并文献复习  

Primary pulmonary mucosa-associated lymphoid tissue lymphoma with dry cough as the only symptom:A case and literature review

作　　者：杨巍 何晨冬 Yang Wei;He Chendong(Department of Radiology,Jiangsu Provincial Hospital of Traditional Chinese Medicine,Affiliated Hospital of Nanjing University of Chinese Medicine,Nanjing 210029,China;Department of Radiology,the First Affiliated Hospital of Bengbu Medical College,Bengbu 233004,China)

机构地区：[1]南京中医药大学附属医院江苏省中医院放射科,江苏南京210029 [2]蚌埠医学院第一附属医院放射科,安徽蚌埠233004

出　　处：《临床荟萃》2023年第7期623-627,共5页Clinical Focus

摘　　要：目的回顾原发性肺黏膜相关淋巴组织淋巴瘤(pulmonary mucosa-associated lymphoid tissue lymphoma,MALT lymphoma)的临床、影像及病理特点,分析误诊原因。方法对1例经病理确诊的原发性肺MALT淋巴瘤的病例资料进行回顾性分析。结果该患者因反复干咳就诊,外院给予抗炎治疗,患者自觉症状有所好转。后症状反复,就诊江苏省中医院,经胸部CT及MRI检查诊断为多中心起源肺腺癌或炎性肉芽肿;行CT引导下经皮肺穿刺活检,术后病理诊断为原发性肺MALT淋巴瘤。结论原发性肺MALT淋巴瘤通常无特异性临床表现,影像学检查难以确诊,抗炎治疗无效时建议活检,有助于避免误诊误治。Objective To review the clinical,imaging,and pathological features of primary pulmonary mucosa-associated lymphoid tissue lymphoma(MALT lymphoma)and analyze the causes of misdiagnosis.Methods A case of primary pulmonary MALT lymphoma confirmed by pathology was analyzed retrospectively.Results The patient had a recurrent dry cough,which was relieved after anti-inflammatory treatment at a local hospital.But then the symptoms recurred,so the patient came to Jiangsu Provincial Hospital of Traditional Chinese Medicine.After chest CT and magnetic resonance imaging(MRI),the patient was diagnosed with multicentric adenocarcinoma or inflammatory granuloma.CT-guided percutaneous lung biopsy was performed,and finally,primary pulmonary MALT lymphoma was diagnosed by pathology.Conclusion Primary pulmonary MALT lymphoma usually has no specific clinical manifestations and is difficult to be diagnosed by imaging examination.The biopsy is recommended when anti-inflammatory therapy is ineffective,which is helpful to avoid misdiagnosis and mistreatment.

关 键 词：淋巴瘤 B细胞 边缘区 肺 干咳 

分 类 号：R733.4[医药卫生—肿瘤]