Urethroplasty in a post irradiation urethral stricture-a review  

作　　者：Carlos Guerra Sergio Davila Slavica Pusica Predrag Aleksic 

机构地区：[1]Department of Urology,Belgrade Center for Genitourinary Reconstructive Surgery,Belgrade 11000,Serbia [2]Department of Urology,Hospital Universitario“Dr.JoséEleuterio González”,Monterrey,Nuevo Leon 64460,Mexico [3]Department of Urology,Medical Military Academy,Belgrade 11000,Serbia

出　　处：《Plastic and Aesthetic Research》2022年第1期133-139,共7页整形与美容研究（英文版）

摘　　要：Radiotherapy-induced urethral strictures(RIUS)decrease quality of life and present a great challenge for surgical reconstruction,especially due to proximal location,compromised vascular supply,and poor wound healing.It is unclear whether urethroplasty is an option in cases with stricture resulting from exposure to pelvic radiation.We review the pathophysiology,diagnostic workup,and disease-specific aspects of RIUS.Furthermore,we discuss several management alternatives such as excision and primary anastomosis,as well as techniques for open reconstruction with flaps.The most extensive techniques in the treatment of strictures include,for example,those using gracilis muscle flaps,as they can involve periurethral tissue to provide sufficient vascularity for excellent post-surgery urethral healing.In brief,RIUS represent a significant challenge.In carefully chosen patients,urethroplasty should be considered as a feasible and durable treatment.However,medical practitioners should always take into consideration that the results of urethroplasty in RIUS are not comparable to urethroplasties without a radiation background.

关 键 词：URETHRA STRICTURE RADIOTHERAPY URETHROPLASTY buccal mucosa graft gracilis muscle flap STRICTURE 

分 类 号：R69[医药卫生—泌尿科学]