镁合金外支架辅助自体牙异位移植  

Magnesium Alloy Stent Assited Autologous Tooth Transplantaion

作　　者：常乾[1] 沈圆 朱可石 李涛[2] 任利玲[1] CHANG Qian;SHEN Yuan;ZHU Keshi;LI Tao;REN Liling(Department of Orthodontics,Hospital of Stomatology Lanzhou University,Lanzhou 730000,Gansu,China;Lanzhou University,Lanzhou 730000,Gansu,China)

机构地区：[1]兰州大学口腔医院口腔正畸科,甘肃兰州730000 [2]兰州大学,甘肃兰州730000

出　　处：《中国美容医学》2023年第8期25-29,共5页Chinese Journal of Aesthetic Medicine

摘　　要：目的:探索微弧氧化处理的镁合金支架辅助自体牙异位移植的可行性。方法:拔除9只雌性比格犬(9~11 kg)的左下颌第二前磨牙、左下颌第三前磨牙和右下颌第二前磨牙,截冠得犬牙根,3Shape扫描形态制作微弧氧化镁合金支架并装配自体牙根,3个月后植入牙槽窝,同时植入1个钛合金种植体和自体牙根进行对照;植入后3、6、12个月分三批处死实验犬,每批3只。截取骨组织标本进行Micro-CT扫描、切片VG染色观察。结果:Micro-CT结果显示,镁合金支架组成骨效果在各时间点均优于钛合金组和自体牙组。VG染色结果可见,无论是在哪个时间点,镁合金支架组的骨接触率均高于钛合金种植体组,自体牙组最低,且差异具有统计学意义(P<0.05)。结论:与自体牙移植和钛合金种植体相比,镁合金支架辅助的自体牙异位移植可以有效促进机体形成新骨,有利于提高移植牙的初期稳定性。Objective This work aims to explore the feasibility of tooth heterotopic transplantaion with micro-arched oxide processed magnesium scaffold.Methods The left mandibular second premolars,the left mandibular third premolars and the right mandibular second premolars of 9 Beagle canine teeth were extracted,then cutting the tooth crowns.The 3Shape scanning morphology was used to make micro-arc magnesium oxide alloy brackets and assemble the autogenous roots.Three months later,they were implanted into the alveolar socket,and a titanium alloy implant and an autogenous root were implanted for comparison.The dogs were killed in three batches at 3,6 and 12 months after implantation.The bone samples were cut for Micro-CT scanning and VG staining of sections for observation.Results The results of micro-CT indicated that The bone composition of magnesium alloy stents is better than titanium alloy group and autologous tooth group at all time points.The result of VG staining indicated that the bone-implant contact of the magnesium alloy group was higher than that of the titanium implant group at any time point,and the autogenous tooth group was the lowest,the difference was statistically significant(P<0.05).Conclusion Compared with autologous tooth heterotopic transplantation and titanium alloy implants,magnesium alloy scaffold assisted tooth transplantation can effectively promote the formation of new bone in the body,which is beneficial to improve the initial stability of the transplanted tooth.

关 键 词：镁合金 自体牙异位移植 动物实验 牙种植体 微弧氧化 支架 

分 类 号：R783.1[医药卫生—口腔医学]