周边视网膜变性广角多模影像研究进展  

Research progress on wide-field multimodal image of peripheral retinal degeneration

作　　者：黄涵 黄琳 彭绍民 马红婕[1,3] Han Huang;Lin Huang;Shao-Min Peng;Hong-Jie Ma(Aier School of Ophthalmology,Central South University,Changsha 410000,Hunan Province,China;Harbin Aier Eye Hospital,Harbin 150000,Heilongjiang Province,China;Guangzhou Aier Eye Hospital,Guangzhou 510000,Guangdong Province,China)

机构地区：[1]中南大学爱尔眼科学院,中国湖南省长沙市410000 [2]哈尔滨爱尔眼科医院,中国黑龙江省哈尔滨市150000 [3]广州爱尔眼科医院,中国广东省广州市510000

出　　处：《国际眼科杂志》2023年第9期1494-1498,共5页International Eye Science

摘　　要：周边视网膜变性是眼科临床常见的病变,不同类型的变性影响不同的视网膜层次,可能对视力造成威胁。尽管现代眼底成像技术被应用于研究其病理生理机制,由于其所处的特殊部位,影像学检查困难,因此发病机制仍不清楚。本文总结了有关周边视网膜变性的多种广角成像技术的影像特征,包括超广角眼底成像、广角频域光学相干断层扫描、光学相干断层扫描血管成像、荧光素眼底血管造影等,及其发病机制或病理特点的新观点,为临床诊疗提供新的思路。由于样本量非常少,且缺乏前瞻性、长期的多模态影像的观察研究,因而目前仍无法全面评价不同类型病变的进展性及危险性。期望在更广的范围内应用多模态广角成像技术对此类疾病进行研究,指导临床干预决策。Peripheral retinal degeneration is a typical lesion in ophthalmic clinical practice.Each type of degeneration affects distinct retinal layers and may lead to sight-threatening complications.Due to its specific location,where current ophthalmic imaging technologies have difficulties observing,the pathogenesis remains unclear despite previous works.This review outlines the characteristics of peripheral retinal degeneration by different wide-field imaging technologies,including ultra-wide field fundus imaging,wide field spectral domain optical coherence tomography,optical coherence tomography angiography and fundus fluorescein angiography,as well as new perspectives on their pathogenesis or pathological characteristics so as to provide new ideas for clinical diagnosis and management.Due to the small size of sample and the lack of prospective and long-term observation of multimodal imaging,it is still impossible to comprehensively evaluate the progression and risk of different types of degeneration.Therefore,it is expected that wide-field multimodal imaging technology will be more widely applied to study the mechanism of peripheral retinal degeneration and guide the clinical practice options.

关 键 词：周边视网膜变性 广角眼底影像 遗传性玻璃体视网膜疾病 发病机制 

分 类 号：R774.1[医药卫生—眼科]