老年短暂性脑缺血发作患者血清生化指标和血脂水平的检测意义探讨  

Significance of detection of serum biochemical indexes and lipid levels in elderly patients with transient ischemic attack

作　　者：孟繁伟 MENG Fan-wei(Biochemical Luminescence Room,Shenyang Jinyu Medical Laboratory Co.,LTD.,Shenyang 110000,China)

机构地区：[1]沈阳金域医学检验所有限公司生化发光室,110000

出　　处：《中国现代药物应用》2023年第16期70-72,共3页Chinese Journal of Modern Drug Application

摘　　要：目的探讨老年短暂性脑缺血发作(TIA)患者血清生化指标和血脂水平的检测意义。方法选取50例已明确诊断的老年TIA患者作为观察组,另选取50例健康体检者作为对照组。检测并比较两组同型半胱氨酸(Hcy)、血清超敏C反应蛋白(hs-CRP)水平及血脂[总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)]水平。结果观察组血清Hcy(16.26±5.31)μmol/L、hs-CRP(26.97±7.99)mg/L明显高于对照组的(9.56±1.62)μmol/L、(2.20±0.45)mg/L,差异具有统计学意义(P<0.05)。观察组TC(5.11±1.40)mmol/L、TG(2.56±0.83)mmol/L、LDL-C(3.37±1.19)mmol/L均高于对照组的(4.09±1.25)、(1.71±0.41)、(2.50±0.88)mmol/L,HDL-C(0.92±0.43)mmol/L低于对照组的(1.40±0.38)mmol/L,差异具有统计学意义(P<0.05)。结论通过分析老年TIA患者血清Hcy、hs-CRP和血脂水平变化,可以评估其脑卒中风险和预后进展情况,具有一定的临床诊断价值。Objective To discuss the significance of detection of serum biochemical indexes and lipid levels in elderly patients with transient ischemic attack(TIA).Methods 50 elderly patients with TIA were selected as the observation group,and 50 healthy subjects were selected as the control group.Detection and comparison were made on levels of homocysteine(Hcy),serum high-sensitivity C-reactive protein(hs-CRP)and blood lipids[total cholesterol(TC),triglyceride(TG),high density lipoprotein cholesterol(HDL-C)and low density lipoprotein cholesterol(LDL-C)]between the two groups.Results Serum Hcy of(16.26±5.31)μmol/L and hs-CRP of(26.97±7.99)mg/L in the observation group were significantly higher than those of(9.56±1.62)μmol/L and(2.20±0.45)mg/L in the control group,and the differences were statistically significant(P<0.05).The observation group had TC of(5.11±1.40)mmol/L,TG of(2.56±0.83)mmol/L and LDL-C of(3.37±1.19)mmol/L,which were higher than those of(4.09±1.25),(1.71±0.41)and(2.50±0.88)mmol/L in the control group;HDL-C of(0.92±0.43)mmol/L in the observation group was lower than that of(1.40±0.38)mmol/L in the control group;the differences were statistically significant(P<0.05).Conclusion By analyzing the changes of serum Hcy,hs-CRP and lipids in elderly patients with TIA,the risk and prognosis of stroke can be assessed,which has certain clinical diagnostic value.

关 键 词：短暂性脑缺血发作 同型半胱氨酸 超敏C反应蛋白 胆固醇 老年 

分 类 号：R743.31[医药卫生—神经病学与精神病学]