合并黄斑劈裂的高度近视患者行有晶状体眼后房型人工晶状体植入术后的临床观察  

Clinical observation of macular foveoschisis in high myopic eyes underwent implantable collamer lens surgery

作　　者：程建宏 潘超[1,2] 谭维娜[1,2] 曾庆延[1,2] 陈茜 CHENG Jianhong;PAN Chao;TAN Weina;ZENG Qingyan;CHEN Qian(Aier Eye Hospital of Wuhan University,Wuhan 430062,Hubei,China;Hankou Aier Eye Hospital,Wuhan 430024,Hubei,China;Hongshan Aier Eye Hospital,Wuhan 430070,Hubei,China)

机构地区：[1]武汉大学附属爱尔眼科医院,湖北武汉430062 [2]武汉爱尔眼科医院汉口医院,湖北武汉430024 [3]武汉爱尔眼科医院洪山医院,湖北武汉430070

出　　处：《武汉大学学报（医学版）》2023年第8期1001-1005,共5页Medical Journal of Wuhan University

基　　金：武汉市医学科研项目(编号:WX21C03);爱尔眼科集团屈光研究所科研基金项目(编号:AR2009D2);爱尔眼科医院集团科研项目(编号:AF1601D4)。

摘　　要：目的:观察合并黄斑劈裂(MF)的高度近视患者行有晶状体眼后房型人工晶状体植入术(ICL)术后的MF的进展情况。方法:采用回顾性研究,将2016年4月至2019年1月行ICL植入术且术前合并MF的高度近视患者15例27只眼纳入本研究。术后随访观察2年,观察的指标包括裸眼视力(UCVA)、最佳矫正视力(BCVA)、黄斑中心凹视网膜厚度(CFT)、视网膜劈裂最厚处厚度(maxRT)、眼轴长度(AL)。采用配对t检验和Bonferroni矫正的重复测量的方差分析对数据进行分析。结果:患者术前平均AL(29.84±2.14) mm,术前等效屈光度(-17.12±2.95) D。术前、术后1年、2年UCVA(logMAR)分别为1.40±0.35、0.15±0.19、0.19±0.23,差异具有统计学意义(F=57.6,P<0.01)。术前、术后1年、2年BCVA(logMAR)分别为0.25±0.16、0.09±0.10、0.09±0.10,差异具有统计学意义(F=7.76,P<0.05)。术前、术后1年、2年CFT分别为(456±15)、(447±13)、(460±13)μm,差异无统计学意义(F=0.37,P>0.05)。术前、术后1年、2年maxRT分别为(677±14)、(654±10)、(667±9)μm,差异无统计学意义(F=0.34,P>0.05)。术后2年平均AL(29.85±2.15) mm,较术前差异无统计学意义(t=-0.28,P>0.05)。结论:合并黄斑劈裂的高度近视患者行ICL植入术后2年随访观察未见黄斑劈裂的显著进展,ICL植入术并未显著增加黄斑劈裂的进展风险。Objective:To observe the progression of macular foveoschisis(MF)in high myopic eyes after implantable collamer lens(ICL)surgery.Methods::The present study was designed as a retrospective study.From April 2016 to January 2019,27 eyes of 15 consecutive high myopic patients with MF who underwent ICL surgery at refractive surgery center were enrolled in the current study.All pa⁃tients had at least 2 years of follow⁃up.Uncorrected visual acuity(UCVA),best corrected visual acu⁃ity(BCVA),central foveal thickness(CFT),maximum retinal thickness(MaxRT),and axial length(AL)were measured.Data were analyzed using paired t⁃test and Bonferroni⁃corrected repeated⁃mea⁃sures analysis of variance.Results::The mean preoperative AL was(29.84±2.14)mm,the mean preoperative spherical equivalent(SE)was(-17.12±2.95)D.The UCVA(LogMAR)preoperative⁃ly,at 1⁃year and 2⁃year postoperatively were 1.40±0.35,0.15±0.19 and 0.19±0.23,respective⁃ly,with statistically significant difference(F=57.6,P<0.01).The BCVA(LogMAR)preoperative⁃ly,at 1⁃year and 2⁃year postoperatively were 0.25±0.16,0.09±0.10 and 0.09±0.10,respective⁃ly,with statistically significant difference(F=7.76,P<0.05).The CFT preoperatively,at 1⁃year and 2⁃year postoperatively were(456±15),(447±13)and(460±13)μm,respectively,without statis⁃tically significant difference(F=0.37,P>0.05).The maxRT preoperatively,at 1⁃year and 2⁃year postoperatively were(677±14),(654±10)and(667±9)μm,respectively,without statistically signif⁃icant difference(F=0.34,P>0.05).The AL at 2⁃year postoperatively was(29.85±2.15)mm,without statistically significant difference as compared with that before operation(t=-0.28,P>0.05).Conclusion::Uncomplicated ICL surgery had no significant effect on the progression of pre⁃ex⁃isting macular foveoschisis in eyes with high myopia up to 24 months of follow⁃up.

关 键 词：有晶状体眼后房型人工晶状体植入术 高度近视 黄斑劈裂 光学相干断层扫描 

分 类 号：R774.5[医药卫生—眼科]