腭裂伤口延迟愈合规律的初期研究  

A preliminary study on delayed wound healing after palatoplasty

作　　者：陈泽华[1] 吴敏[1] 刘颖蒙 龚彩霞[1] 石冰[1] 黄汉尧 Zehua Chen;Min Wu;Yingmeng Liu;Caixia Gong;Bing Shi;Hanyao Huang(State Key Laboratory of Oral Diseases&National Clinical Research Center for Oral Diseases&Department of Cleft Lip and Palate Surgery,West China Hospital of Stomatology,Sichuan University,Chengdu 610041,China)

机构地区：[1]口腔疾病研究国家重点实验室、国家口腔疾病临床医学研究中心、四川大学华西口腔医院唇腭裂外科,成都610041

出　　处：《中华口腔医学研究杂志（电子版）》2023年第1期45-48,共4页Chinese Journal of Stomatological Research(Electronic Edition)

基　　金：四川省自然科学基金(2022NSFSC0743);四川大学华西口腔医院探索与研发项目(RD-02-202107)。

摘　　要：目的研究腭裂术后伤口延迟愈合的变化规律。方法2017年4月至2019年12月在四川大学华西口腔医院唇腭裂外科行一期腭裂整复术,并且术后发生伤口延迟愈合的患者150例,分析腭裂伤口在延迟愈合的情况下,术后6个月内延迟愈合的变化规律及其影响因素。结果当伤口延迟愈合的部位分别发生在硬腭、硬软腭交界和软腭时,其最终形成的腭瘘分别占各部位延迟愈合总病例数的38.1%、9.8%和6.7%,差异有统计学意义(χ^(2)=52.962,P<0.001)。当伤口延迟愈合的伤口面积分别为≤0.5 cm^(2)、>0.5~≤1.0 cm^(2)、>1.0~≤1.5 cm^(2)和>1.5 cm^(2)时,其最终形成的腭瘘分别占各伤口面积总病例数的5.6%、14.8%、35.8%和44.9%,差异有统计学意义(χ^(2)=28.068,P<0.001)。其余相关影响因素如年龄、性别、腭裂类型等,差异均无统计学意义。结论腭裂术后出现延迟愈合的伤口,其最终是否形成腭瘘受伤口发生部位及伤口大小影响。Objective To study the regularity of the delayed wound healing after cleft palate repair.Methods From April 2017 to December 2019,a total of 150 patients with delayed wound healing after primary cleft palate repair were included in the Department of Cleft Lip and Palate Surgery,West China Hospital of Stomatology,Sichuan University.The changing regularity and influencing factors of delayed wound healing within 6 months after cleft palate repair were analyzed.Results When the sites of delayed wound healing occurred at the hard palate,the junction of hard and soft palate,and the soft palate,the final formation of palatal fistula accounted for 38.1%,9.8%and 6.7%,respectively,of the total number of delayed wound healing cases at each site,and the differences were statistically significant(χ^(2)=52.962,P<0.001).When the wound areas of delayed wound healing were≤0.5 cm^(2),>0.5-≤1.0 cm^(2),>1.0-≤1.5 cm^(2)and>1.5 cm^(2),the final formation of palatal fistula accounted for 5.6%,14.8%,35.8%and 44.9%,respectively,of the total cases of each wound area,and the differences were statistically significant(χ^(2)=28.068,P<0.001).There was no difference in other related factors such as age,gender and cleft palate type.Conclusion Delayed wound healing after primary cleft palate repair may be correlated to the sites and size of the wound.

关 键 词：腭裂 伤口 延迟愈合 规律 

分 类 号：R78[医药卫生—口腔医学]