女性乳腺癌发病与体力活动的相关性分析  

Correlation analysis of female breast cancer incidence and physical activity

作　　者：王景 刘林[2] Wang Jing;Liu Lin(Department of Breast Surgery,Beijing Tongzhou Maternal and Child Health Hospital,Beijing 101100,China)

机构地区：[1]北京市通州区妇幼保健院乳腺科,101100 [2]解放军总医院第一医学中心普外学部

出　　处：《中华保健医学杂志》2023年第4期419-421,共3页Chinese Journal of Health Care and Medicine

摘　　要：目的探讨女性乳腺癌发病与体力活动的相关性。方法采取医院为基础的病例对照研究,选取2015年1月~2018年12月在本院就诊的162例乳腺癌患者为观察组,对照组为同时期接受治疗的在本地居住时间超过5年的162例无恶性肿瘤史的女性患者。比较两组患者体力活动情况和相关危险因素,采用logistic回归分析评估对女性乳腺癌发病的影响。结果多因素logistic回归分析结果显示,有口服避孕药史(OR=1.510,95%CI=1.051~2.170)、有一级亲属肿瘤史(OR=1.523,95%CI=1.094~2.122)、蔬菜摄入≤250 g∕d(OR=1.464,95%CI=1.019~2.103)、水果摄入≤250 g∕d(OR=1.456,95%CI=1.030~2.060)、有吸烟史(OR=1.495,95%CI=1.044~2.140)为女性乳腺癌发病的危险因素,体育活动增加(OR=0.668,95%CI=0.490~0.911)、职业性体力活动增加(OR=0.663,95%CI=0.480~0.916)为保护性因素(P<0.05)。结论职业性体力活动及体育活动是女性乳腺癌发病的保护因素,另外蔬菜摄入≤250 g∕d、水果摄入≤250 g∕d、口服避孕药史、有一级亲属肿瘤史及吸烟史是女性乳腺癌发病的危险因素。Objective To explore the correlation between the incidence of breast cancer in women and physical activity.Methods This study adopted a hospital-based case-control study.162 breast cancer patients who were treated in our hospital from January 2015 to December 2018 were selected as the case group,and the control group was the local patients who received treatment in our hospital during the same period.There were 162 female patients with no history of malignant tumors who lived for more than 5 years.Collected the general data of the two groups of patients,compared the above-mentioned data of the two groups of patients,and used logistic regression analysis to evaluate the impact of the above indicators on the incidence of female breast cancer.Results The result of multivariate logistic regression analysis based on univariate analysis showed that:history of oral contraceptives(OR=1.510,95%CI=1.051~2.170),history of tumors in first-degree relatives(OR=1.523,95%CI=1.094~2.122),Vegetable intake≤250 g∕d(OR=1.464,95%CI=1.019~2.103),fruit intake≤250 g∕d(OR=1.456,95%CI=1.030~2.060),smoking history(OR=1.495,95%CI=1.044~2.140)were the risk factors for breast cancer in women,increased physical activity(OR=0.668,95%CI=0.490~0.911),occupational physical activity increased(OR=0.663,95%CI=0.480~0.916)were protective factors(P<0.05).Conclusion Occupational physical activity and physical activity are the protective factors of female breast cancer,In addition,Intake of vegetables≤250 g∕d,intake of fruits≤250 g∕d,history of oral contraceptives,history of cancer in first-degree relatives and smoking were the risk factors of breast cancer.

关 键 词：女性 乳腺癌 体力活动 相关性 

分 类 号：R737.9[医药卫生—肿瘤]