Projections from the Prefrontal Cortex to Zona Incerta Mediate Fear Generalization  

作　　者：Kun Tong Guang-Kai Bu Si-Qi Jing Tong Wu Yu-Tong Song Yue You Le Liu Yuan-Hao Chen Jing-Ru Hao Nan Sun Can Gao 

机构地区：[1]NMPA Key Laboratory for Research and Evaluation of Narcotic and Psychotropic Drugs,Jiangsu Province Key Laboratory of Anesthesiology,Jiangsu Province Key Laboratory of Anesthesia and Analgesia Application,Xuzhou Medical University,Xuzhou 221004,China [2]Jiangsu Province Key Laboratory of Brain Disease and Bioinformation,Research Center for Biochemistry and Molecular Biology,Xuzhou Medical University,Xuzhou 221004,China [3]Department of Anesthesia,The Afliated Hospital of Xuzhou Medical University,Xuzhou 221002,China [4]School of Life Sciences,Xuzhou Medical University,Xuzhou 221004,China

出　　处：《Neuroscience Bulletin》2023年第7期1151-1156,共6页神经科学通报（英文版）

基　　金：supported by grants from the National Natural Science Foundation of China(81870852 and 82171199);the Qing Lan Project of Jiangsu Province,the Education Department of Jiangsu Province(18KJA320007);the Natural Science Foundation of Jiangsu Province(BK20181146 and BK20210911);the Postgraduate Research&Practice Innovation Program of Jiangsu Province(KYCX21_2706,KYCX21_2703,and YCX21_2717);the Program on Basic Research Projects of Xuzhou City(KC21048);the Special Funds for Anesthesia Medical Research of Jiangsu Medical Association SYH-32021-0040(2021035).

摘　　要：Dear Editor,Depending on the perceived threat in the environment,organisms can express a broad spectrum of behaviors,ranging from exploration to defensive behaviors[1,2],such as fear response and avoidance.Generalization of fear memory can generate anxiety-related disorders that afflict 10%-30%of individuals worldwide,especially during the epidemic situation[3,4].

关 键 词：CORTEX SPECTRUM GENERA 

分 类 号：R749.5[医药卫生—神经病学与精神病学]