偏头痛与Willis环变异和炎症的关联性研究  

Relationship between migraine and Willis ring variation and inflammation

作　　者：张艳华[1] Zhang Yanhua(Luohe Central Hospital,Luohe,Henan 462005)

机构地区：[1]漯河市中心医院,河南漯河462005

出　　处：《辽宁医学杂志》2023年第3期38-40,共3页Medical Journal of Liaoning

摘　　要：目的 偏头痛与Willis环变异和炎症介质的相关性研究。方法 回顾性分析我院2018年3月至2020年8月收治的87例偏头痛患者为观察组,选取同期91例健康体检者为对照组。观察两组患者Willis不完整性发生率比较,同型半胱氨酸(Homocysteine, HCY)含量及C-反应蛋白(C-reaction protein, CRP)浓度比较及观察组HCY、CRP相关性分析。结果 观察组Willis环不完整性、前部不完整发生率及后部不完整性发生率均高于对照组(P<0.05)。观察组HCY含量和CRP浓度高于对照组(P<0.05)。观察组HCY、CRP无相关性。结论 Willis环变异可引发偏头痛,同时HCY、CRP增高,但两者无相关性。Objective To study the correlation between migraine,Willis circle variation and inflammatory mediators.Methods A retrospective analysis was conducted in 87 migraine patients(the observation group)admitted to our hospital from March 2018 to August 2020,and 91 healthy patients during the same period were selected as the control group.The comparison of the incidence of Willis incompleteness,the comparison of homocysteine(HCY)content and C-reaction protein(CRP)concentration between the two groups of patients,and the correlation analysis of HCY and CRP in the observation group were observed.Results The incidence of incompleteness and posterior incompleteness of the circle of Willis in the observation group was higher than that in the control group(P<0.05),but there was no significant difference in the incidence of the incompleteness of the anterior part of the circle of Willis between the two groups(P>0.05).The HCY content and CRP concentration of the observation group were higher than those of the control group(P<0.05).There was no correlation between HCY and CRP in the observation group.Conclusion Migraine can cause Willis circle variation and elevated HCY and CRP levels,but there is no correlation between the two levels.

关 键 词：偏头痛 WILLIS环 炎症介质 

分 类 号：R747.2[医药卫生—神经病学与精神病学]