Recent advances of implantable systems and devices in cancer therapy and sensing  

作　　者：Zhuoheng Jiang Zhaoyang Yue Zhirong Liu Linlin Li 

机构地区：[1]Beijing Institute of Nanoenergy and Nanosystems,Chinese Academy of Sciences,Beijing 101400,China [2]School of Nanoscience and Technology,University of Chinese Academy of Sciences,Beijing 100049,China [3]School of Chemistry and Chemical Engineering,Center on Nanoenergy Research,School of Physical Science and Technology,Guangxi University,Nanning 530004,China

出　　处：《Nano Research》2023年第9期11653-11666,共14页纳米研究（英文版）

基　　金：supported by the National Nature Science Foundation of China(Nos.82072065 and 82202333);the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDA16021103);the Fundamental Research Funds for the Central Universities(Nos.E2EG6802X2 and E2E46801);the China Postdoctoral Science Foundation(Nos.BX2021299 and 2021M703166);the National Youth Talent Support Program.

摘　　要：Malignant tumors have the capability to metastasize and colonize,meaning that they can spread to other organs and tissues,distributing metastatic focus and are hard to target.Although significant advances have been made in cancer treatment,it remains one of the leading causes of death around the globe.In recent years,new-emerging implantable systems and devices have been developed to tackle the challenge of metastatic tumors.In this review,implantable systems for suppressing tumors and preventing tumor recurrence are reported.In particular,we emphasize the responsive drug delivery systems and the external field assisted catalytic therapy for tumor treatment,as well as implantable biosensors for tumor microenvironment monitoring.We also conclude the open challenges and future perspectives of implantable systems and devices for cancer therapy and sensing.

关 键 词：implantable devices cancer therapy drug delivery BIOSENSOR NANOGENERATOR 

分 类 号：R730.5[医药卫生—肿瘤]