4种口腔修复材料对咀嚼及牙龈功能的影响  

Effect of 4 kinds of prosthodontic materials on masticatory and gingival function

作　　者：王怡婷 文少敏[2] 李小红 李苑荟 WANG Yi-ting;WEN Shao-min;LI Xiao-hong;LI Wan-hui(Department of Stomatology,Haikou Third People's Hospital.Haikou 571199;Department of Oral Restoration,The First Affiliated Hospital of Hainan Medical University.Haikou 570100,Hainan Province,China)

机构地区：[1]海口市第三人民医院口腔科,海南海口571199 [2]海南医学院第一附属医院口腔修复科,海南海口570100

出　　处：《上海口腔医学》2023年第4期405-409,共5页Shanghai Journal of Stomatology

基　　金：海南省卫生健康行业科研项目(20A200250)。

摘　　要：目的 :探讨4种口腔修复材料对咀嚼及牙龈功能的影响。方法 :收集2019年10月—2022年1月行口腔修复治疗的167例牙体缺损患者,随机分为4组,即纯钛组41例、钴铬合金组40例、镍铬合金组43例和二氧化锆组43例。记录4组治疗后6个月疗效及满意度,记录并比较4组治疗前及治疗后6个月的咀嚼功能(咀嚼效率、咬合力)和牙龈功能[菌斑指数(plaque index, PLI)、牙龈指数(gingival index, GI)、龈沟出血指数(sulcus bleeding index, SBI)]、龈沟液炎症相关指标[肿瘤坏死因子(tumor necrosis factor alpha, TNF-α)、白介素6 (interleukin-6, IL-6)、天冬氨酸转氨酶(aspartate aminotransferase, AST)及碱性磷酸酶(alkaline phosphatase, ALP)]。采用SPSS 20.0软件包对数据进行统计学分析。结果:4组的疗效具有可比性(P>0.05)。治疗前后,4组的咀嚼效率和咬合力具有可比性(P>0.05),与治疗前比,治疗后4组的咀嚼效率和咬合力显著增高(P<0.05)。治疗前,4组的PLI、GI、SBI、龈沟液重量、龈沟液中TNF-α、IL-6、AST和ALP具有可比性(P>0.05),与治疗前比,治疗后4组的PLI、GI和SBI显著降低(P<0.05),降低顺序为钴铬合金组≈镍铬合金组<纯钛组<二氧化锆组。治疗前,4组的龈沟液重量、龈沟液中TNF-α、IL-6、AST和ALP具有可比性(P>0.05),与治疗前比,治疗后4组的龈沟液重量、龈沟液中TNF-α、IL-6、AST和ALP显著增高(P<0.05),增高顺序为二氧化锆组<纯钛组<钴铬合金组≈镍铬合金组。4组的修复体完整性、颜色满意度具有可比性(P>0.05),4组的边缘适合性、敏感性满意度差异显著(P<0.05)。结论:纯钛、钴铬合金、镍铬合金及二氧化锆均可用于牙体缺损治疗,可获得满意的咀嚼功能;但与纯钛、钴铬合金、镍铬合金相比,二氧化锆具有改善牙龈功能及龈沟液炎症的作用,具有更广阔的应用前景。PURPOSE:To investigate the effect of 4 kinds of prosthodontic materials on masticatory and gingival function.METHODS:A total of 167 patients with dental defects who underwent prosthodontic treatment from October 2019 to January 2022 were collected.They were randomly divided into 4 groups with 41 cases in the pure titanium group,40 cases in the cobalt-chromium alloy group,43 cases in the nickel-chromium alloy group and 43 cases in the zirconium dioxide group.The curative effect and satisfaction degree after 6 months of treatment in 4 groups were recorded and compared.The masticatory function(chewing efficiency,bite force),gingival function[plaque index(PLI),gingival index(GI)and sulcus bleeding index(SBI)],gingival crevicular fluid inflammation-related indicators[tumor necrosis factor alpha(TNF-α),interleukin-6(IL-6),aspartate aminotransferase(AST)and alkaline phosphatase(alkaline phosphatase,ALP)]before and after treatment were measured and compared in 4 groups.Statistical analysis was performed with SPSS 20.0 software package.RESULTS:There was no significant difference in curative effect in 4 groups(P>0.05).Before and after treatment,there was no significant difference in mastication efficiency and bite force in 4 groups(P>0.05).Before treatment,there was no significant difference in PLI,GI,SBI,gingival crevicular fluid weight,TNF-α,IL-6,AST and ALP in gingival crevicular fluid in 4 groups(P>0.05).Compared with before treatment,PLI,GI and SBI in 4 groups were decreased after treatment(P<0.05),and the decrease was in the order of cobalt-chromium alloy group≈nickel-chromium alloy group<pure titanium group<zirconia dioxide group.Before treatment,there was no significant difference in the weight of gingival crevicular fluid,TNF-α,IL-6,AST and ALP in gingival crevicular fluid in 4 groups(P>0.05).The crevicular fluid weight,TNF-α,IL-6,AST and ALP in gingival crevicular fluid were significantly increased(P<0.05),and the increase was in the order of zirconia group<pure titanium group<cobalt-chromium alloy group≈

关 键 词：牙体缺损 口腔修复材料 咀嚼功能 牙龈功能 

分 类 号：R783.3[医药卫生—口腔医学]