Sidearm as a Control in the Asymmetric Ring Opening Reaction of Donor-Acceptor Cyclopropane  

作　　者：Qikai Kang Lijia Wang Zhongbo Zheng Junfang Li Yong Tang 

机构地区：[1]State Key Laboratory of Organometallic Chemistry,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032,China

出　　处：《Chinese Journal of Chemistry》2014年第8期669-672,共4页中国化学（英文版）

基　　金：We are grateful for the financial support from the Natural Science Foundation of China(Nos.21121062,and 21272250),and Chinese Academy of Sciences.

摘　　要：A new type of trisoxazoline and bisthiazoline based ligands have been developed,which are absent of chiral motif on the parent skeleton and containa chiral backbone on sidearm.The ligands promote the amine nucleophilic ring opening reaction of 1,1-cyclopropane diesters smoothly,furnishing the γ-amino acid derivatives in high yield with moderate to good enantioselectivity.

关 键 词：sidearm OXAZOLINE ASYMMETRIC ring opening CYCLOPROPANE 

分 类 号：O62[理学—有机化学]