OXAZOLINE

作品数:47被引量:23H指数:3
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相关领域:理学更多>>
相关作者:李晋文高雅杰马淑金李艳芳王杏林更多>>
相关机构:北京大学南开大学北京大学第三医院天津药物研究院更多>>
相关期刊:《Science China Chemistry》《应用化学》《Chemical Research in Chinese Universities》《Science China Materials》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划上海市自然科学基金国家教育部博士点基金更多>>
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Tuning lanthanide luminescence from bipyridine-bis(oxazoline/thiazoline)tetradentate ligands
《Chinese Journal of Structural Chemistry》2024年第9期46-51,共6页Hao Jiang Yuan-Yuan He Hai-Chao Liang Meng-Jia Shang Han-Han Lu Chun-Hua Liu Yin-Shan Meng Tao Liu Yuan-Yuan Zhu 
supported by the National Natural Science Foundation of China(Nos.22371063,22222103,22173015,22025101,and 91961114);the State Key Laboratory of Fine Chemicals at Dalian University of Technology(KF 1607);the Fundamental Research Funds for the Central Universities of China(PA2021GDSK0063,DUT22LAB606).
Organic ligands play a pivotal role in lanthanide luminescence by acting as sensitizers for energy absorption and transfer,a phenomenon known as the fluorescence antenna effect.Herein,we introduce two tetradentate nit...
关键词:LANTHANIDE Luminescence Antenna effect EUROPIUM TERBIUM 
Synthesis and crystal structure of axial chiral-chiral oxazoliline ligands
《分子科学学报》2024年第4期348-352,共5页YANG Wendeng YANG Fa LIANG Zhengyun WANG Yin XIE Meijie WU Guixian CHEN Minghua 
supported by Guizhou Province College Students Innovation Project(S202310666114);the Student Program of Minzu Normal University of Xingyi(23XYXS28);Guizhou Province Qianxinan Prefecture Science and Technology Bureau project(2022-1-24).
Seven 2,2'-bipyridine-based oxazole derivatives have been synthesized through multi-step reactions using 2,2'-bipyridine-3,3'-dicarboxylic acid as raw material.The structures of compounds 1-6 were characterized by usi...
关键词:2 2'-bipyridine-3 3'-dicarboxylic acid chiral β-aminoalcohols axial chiral compound axial chiral-chiral oxazoline ligand crystal structure 
抗原改造联合纳米肿瘤疫苗用以克服肿瘤新抗原短缺及在多种肿瘤类型上激起强效抗肿瘤免疫反应被引量:1
《Science Bulletin》2024年第7期922-932,共11页陈宏宇 黄子超 李佳玄 董思 徐玉笛 马胜 赵佳雨 刘丽萍 孙天盟 宋万通 陈学思 
supported by the National Natural Science Foundation of China (22222509, 52025035, 52103194, and 22105199);The Ministry of Science and Technology of China (2022YFE0110200);Bureau of International Cooperation Chinese Academy of Sciences (121522KYSB20200029);Jilin Province Science and Technology Development Plan (YDZJ202101ZYTS131, 20220402037GH, and 20210508049RQ);Jilin Provincial International Cooperation Key Laboratory of Biomedical Polymers (20210504001GH);The Youth Innovation Promotion Association of Chinese Academy of Sciences (2020232)。
Neoantigen cancer vaccines have been envisioned as one of the most promising means for cancer therapies.However,identifying neoantigens for tumor types with low tumor mutation burdens continues to limit the effectiven...
关键词:Cancer immunotherapy Cancer vaccine NEOANTIGEN NANOCARRIER Poly(2-oxazoline)s 
模拟宿主防御肽的聚(2-噁唑啉)作为佐剂增强多粘菌素B的抗菌活性并拓展抗菌谱
《Science China Materials》2024年第3期991-999,共9页罗政杰 赵学斌 周敏 邹景橙 肖希勉 刘龙强 谢佳洋 武月铭 张雯静 刘润辉 
supported by the National Key Research and Development Program of China (2022YFC2303100);the National Natural Science Foundation of China (T2325010, 22305082, 52203162, and 22075078);Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism (Shanghai Municipal Education Commission);the Program of Shanghai Academic/Technology Research Leader (20XD1421400);the Open Research Fund of the State Key Laboratory of Polymer Physics and Chemistry (Changchun Institute of Applied Chemistry, Chinese Academy of Sciences);the Open Project of Engineering Research Center of Dairy Quality and Safety Control Technology (Ministry of Education, R202201);China National Postdoctoral Program for Innovative Talents (BX2021102);China Postdoctoral Science Foundation (2022M710050);the support of the Analysis and Testing Center of School of Chemical Engineering, East China university of Science and Technology。
临床上常用的广谱抗生素无法有效解决抗生素高度耐药ESKAPE菌感染的难题,ESKAPE耐药菌已经成为人类生命健康的重大威胁.抗生素与佐剂的联合治疗是解决抗生素耐药菌感染的重要途径,但是探索对所有ESKAPE耐药菌都具有广谱和高效抗菌活性...
关键词:poly(2-oxazoline)s ESKAPE bacteria polymyxin B broad-spectrum activity 
Dual-functional poly(2-methyl-2-oxazoline)/poly(2-(dimethylamine)ethyl methacrylate)mixed brushes with switchable protein adsorption and antibacterial properties
《Chinese Journal of Chemical Engineering》2024年第2期19-30,共12页Kang He Liangyu Zhu Yanmei Wang 
the financial support of the National Natural Science Foundation of China(21674102)。
Herein,binary mixed brushes consisting of poly(2-methyl-2-oxazoline)(PMOXA)and poly(2-(dimethylamine)ethyl methacrylate)(PDMAEMA)with different chain lengths were fabricated by successive grafting of NH_(2)-terminated...
关键词:Switchable conformation transition Controllable protein adsorption Mixed brushes Isoelectric point Antibacterial surface 
Effects of π-conjugation-substitution on ESIPT process for oxazoline-substituted hydroxyfluorenes
《Chinese Physics B》2023年第2期499-503,共5页汪迪 周悄 魏强 宋朋 
supported by the National Natural Science Foundation of China (Grant No. 11974152);the Shenyang High level Innovative Talents Program (Grant No. RC200565);the Science program of Liaoning Provincial Department of Education (Grant No. LJKZ0097);the Intercollegiate cooperation project of colleges and universities of Liaoning Provincial Department of Education。
Excited-state intramolecular proton transfer(ESIPT) molecules are broadly applied to UV absorbers, fluorescence sensing, and lighting materials. In previous work, the fluorescence colors of oxazoline-substituted hydro...
关键词:density functional theory(DFT)and time-dependent DFT(TDDFT) excited-state proton transfer intramolecular hydrogen bonding π-conjugation-substitution 
Nucleobase-crosslinked poly(2-oxazoline) nanoparticles as paclitaxel carriers with enhanced stability and ultra-high drug loading capacity for breast cancer therapy被引量:2
《Asian Journal of Pharmaceutical Sciences》2022年第4期571-582,共12页Si Dong Sheng Ma Hongyu Chen Zhaohui Tang Wantong Song Mingxiao Deng 
financially supported by the National Natural Science Foundation of China (51973215, 52025035, 52103194, 22105199, 51829302);Bureau of International Cooperation Chinese Academy of Science (121522KYSB20200029);the Youth Innovation Promotion Association of Chinese Academy of Sciences (2020232)
Poly(2-oxazoline)(POx)has been regarded as a potential candidate for drug delivery carrier to meet the challenges of nanomedicine clinical translation,due to its excellent biocompatibility and self-assembly properties...
关键词:Poly(2-oxaozoline) NANOPARTICLES PACLITAXEL Nucleobase-crosslinked Murine breast cancer 
Synthesis of Chiral Hydantoins and Thiazolidinediones via Iridium-Catalyzed Asymmetric Hydrogenation
《Chinese Journal of Chemistry》2022年第7期819-824,共6页Yu Nie Jing Li Qianjia Yuan Wanbin Zhang 
supported by the National KeyR&D Programof China(No.2018YFE0126800);National Natural Science Foundation of China(Nos.22001164,21620102003 and 21991112);Shanghai Municipal Education Commission(No.201701070002E00030);Shanghai Pujiang Program(20PJ1406400);the startup funding from Shanghai Jiao Tong University。
Herein,we report an iridium-catalyzed asymmetric hydrogenation of hydantoin and thiazolidinedione derived exocyclic alkenes using our developed BiphPHOX as a ligand.The transformation shows good functional group toler...
关键词:HYDANTOINS THIAZOLIDINEDIONES Phosphine-oxazoline ligand IRIDIUM Asymmetric catalysis 
Palladium-catalyzed direct construction of oxazoline-containing polycyclic scaffolds via tandem addition/cyclization of nitriles and arylboronic acids被引量:1
《Organic Chemistry Frontiers》2022年第1期123-128,共6页Shu-Qiang Cui Na Cheng Qian-Qian Ma Zhong-Lin Wei Wei-Wei Liao 
The NSFC(no.21772063);the Open Project of State Key Laboratory for Supramolecular Structure and Materials(sklssm2021010)are acknowledged.
An efficient construction of oxazoline-containing polycyclic scaffolds is presented through a Pd-catalyzed addition/cyclization of(hetero)arene tethered O-acyl cyanohydrin units and arylboronic acids.Diverse oxazoline...
关键词:conditions boron catalyzed 
Functional Amphiphilic Poly(2-oxazoline)Block Copolymers as Drug Carriers:the Relationship between Structure and Drug Loading Capacity被引量:4
《Chinese Journal of Polymer Science》2021年第7期865-873,共9页Si Dong Sheng Ma Zhi-Lin Liu Li-Li Ma Yu Zhang Zhao-Hui Tang Ming-Xiao Deng Wan-Tong Song 
the National Natural Science Foundation of China(Nos.51673185,51973215,51673189,51829302,52003268 and 52025035);as well as the support from the Youth Innovation Promotion Association of Chinese Academy of Sciences(No.2020232).
Poly(2-oxazoline)(POx)is a kind of polymeric amides that can be viewed as conformational isomers of polypeptides with excellent cyto-and hemo-compatibility,and is promising to be used as drug carriers.However,the drug...
关键词:Poly(2-oxaozoline) Polymeric micelles Drug loading π-πInteraction Electrostatic interaction 
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