supported by the National KeyR&D Programof China(No.2018YFE0126800);National Natural Science Foundation of China(Nos.22001164,21620102003 and 21991112);Shanghai Municipal Education Commission(No.201701070002E00030);Shanghai Pujiang Program(20PJ1406400);the startup funding from Shanghai Jiao Tong University。
Herein,we report an iridium-catalyzed asymmetric hydrogenation of hydantoin and thiazolidinedione derived exocyclic alkenes using our developed BiphPHOX as a ligand.The transformation shows good functional group toler...
Supported by the National Natural Science Foundation of China(No.21342002).
The Mannich reaction of various 5-substituted and N-acyl substituted chiral hydantoins with a series of aldimines smoothly occurred with full stereochemical control. These Mannich adducts have been cleaved by alcoholy...
The reduction of various hydantoins with sodium borohydride gave the corresponding 4-hydroxy- 2-imidazolidinones in high yields. In contrast, reduction employing a boron trifluoride etherate-sodium borohydride system ...
Diastereoselective conjugate addition of 1-enoyl-5-substituted hydantoins with allyltrimethylsilane in the presence of Ti(IV) chloride proceeded to give the corresponding allyl adducts in high yield and high diastereo...
Project (NO. 29770511) suported by the National Natural Science Foundation of China.
Using acrylamide as hydrogen bonding functional monomer and (5R)-5-benzylhydantoin as template, a molecularly imprinted polymer was prepared in a polar solvent, which exhibited good enantiomeric recognition properties...