N-Heterocyclic Carbene-Catalyzed All Carbon-[4+2] Cyclocondensation of α,β-Unsaturated Acyl Chlorides with 3-Alkylenyloxindoles  

作　　者：Litao Shen Wenqiang Jia Song Ye 

机构地区：[1]Beijing National Laboratory for Molecular Sciences,CAS Key Laboratory of Molecular Recognition and Function,Institute of Chemistry,Chinese Academy of Sciences,Beijing 100190,China

出　　处：《Chinese Journal of Chemistry》2014年第8期814-818,共5页中国化学（英文版）

基　　金：Financial support from National Natural Science Foundation of China(No.21272237);the Ministry of Science and Technology of China(No.2011CB808600);the Chinese Academy of Sciences is gratefully acknowledged.

摘　　要：Although the NHC-catalyzed cyclization reactions have been well established for the synthesis of various heterocycles,the corresponding all carbon cyclization reaction for the synthesis of carbocycles is far less established.In this note,the NHC-catalyzed all carbon[4+2]cyclocondensation of α,β-unsaturated acyl chlorides and 3-alkenyloxindoles was developed to give the corresponding spirocarbocyclic oxindoles in good yield with good to high diastereoselectivities.

关 键 词：N-heterocyclic carbene catalysis CYCLOCONDENSATION spirocyclic oxindoles hexenones CARBOCYCLES 

分 类 号：O62[理学—有机化学]