肝胆胰恶性肿瘤长程化管理的思考与实践  

Thought and practice of long-term management for hepatobiliary and pancreatic malignant tumors

作　　者：孙玉岭[1] 朱荣涛[1] 王维杰[1] Sun Yuling;Zhu Rongtao;Wang Weijie(Department of Hepatobiliary and Pancreatic Surgery,the First Affiliated Hospital of Zhengzhou University,Institute of Hepatobiliary and Pancreatic Diseases of Zhengzhou University,Zhengzhou Basic and Clinical Key Laboratory of Hepatopancreatobiliary Diseases,Zhengzhou 450052,China)

机构地区：[1]郑州大学第一附属医院肝胆胰外科、郑州大学肝胆胰疾病研究所、郑州市肝胆胰疾病基础及临床重点实验室,郑州450052

出　　处：《中华肝胆外科杂志》2023年第7期486-492,共7页Chinese Journal of Hepatobiliary Surgery

基　　金：国家自然科学基金(82172944、81870457、81900558)。

摘　　要：手术切除是肝胆胰肿瘤患者获得治愈的有效手段,综合运用内镜、介入、放疗及系统性治疗等手段不仅能显著提高疾病的早期诊断率,使部分交界可切除肿瘤患者成功降期行根治性切除,又能降低肿瘤复发率,延长患者生存期。近年来,系统性治疗新药不断涌现为肝胆胰恶性肿瘤患者带来新机遇,但是,诊疗医师也随之增多。因此,以治疗手段为主的分科诊疗体制与实现规范有序的治疗间的矛盾愈发突出。根据国内外肝胆胰恶性肿瘤研究的最新进展,并结合自身的临床经验,笔者提出了基于肝胆胰综合技术诊疗团队的长程化管理理念,对肝胆胰恶性肿瘤患者的诊疗进行新的思考和实践。Radical resection is the only measurement to cure patients of hepatobiliary and pancreatic tumors.The comprehensive application of endoscopy,interventional therapy,radiotherapy and systemic therapy can not only significantly improve the early diagnosis rate of the disease,and successfully transform some borderline resectable tumors into radical resectable states,but also reduce the recurrence rate of tumors after surgery,thus prolonging the survival time of patients.In recent years,the continuous emergence of new systemic therapeutic drugs has brought new opportunities for patients with hepatobiliary and pancreatic malignancies,but the number of doctors participating in diagnosis and treatment has also increased accordingly.Therefore,the contradiction between the division system based on treatment methods and the orderly and standardized treatment is becoming more and more prominent.According to the latest progress of hepatobiliary and pancreatic cancer research at home and abroad,and combined with our clinical experience,we proposed a long-term management concept based on hepatobiliary and pancreatic comprehensive multi-technical team.Based on this concept,we have carried out new thought and practice on the diagnosis and treatment of patients with hepatobiliary and pancreatic malignant tumors.

关 键 词：肝肿瘤 胆道肿瘤 胰腺肿瘤 长程化管理 综合技术诊疗团队 

分 类 号：R735[医药卫生—肿瘤]