超声内镜引导下内引流与经皮穿刺引流治疗胰腺假性囊肿疗效比较的荟萃分析  

A meta-analysis on the comparison between endoscopic ultrasound-guided drainage and percutaneous drainage for treating pancreatic pseudocyst

作　　者：李丛祥 张艳青[1] 赵军 田淑妮 郭安兵 鲁临[3] 彭利军[3] Li Congxiang;Zhang Yanqing;Zhao Jun;Tian Shuni;Guo Anbing;Lu Lin;Peng Lijun(Clinical Medical College,Weifang Medical University,Weifang 261053,China;Department of Spleen and Stomach Diseases,Zaozhuang Hospital of Traditional Chinese Medicine,Zaozhuang 277000,China;Department of Gastroenterology,Linyi People′s Hospital,Linyi 276000,China)

机构地区：[1]潍坊医学院临床医学院,潍坊261053 [2]枣庄市中医医院脾胃病科,枣庄277000 [3]临沂市人民医院消化内科,临沂276000

出　　处：《中华胰腺病杂志》2023年第4期283-289,共7页Chinese Journal of Pancreatology

基　　金：山东省医药卫生科技发展计划(202003031137);临沂市科技发展计划(202020005)。

摘　　要：目的荟萃分析超声内镜引导下内引流(EUS-GD)和经皮穿刺引流(PD)治疗胰腺假性囊肿(PPC)的疗效。方法以胰腺假性囊肿、超声内镜、置管引流、pancreatic pseudocyst、endoscopic ultrasonography、endoscopic ultrasound-guided、EUS、EUS-guided、percutaneous drainage为检索词,检索中国知网、万方医学网、PubMed、Web of Science数据库,检索时限从建库至2021年10月1日。搜索关于PD、超声内镜和PPC的回顾性队列研究,按照纳入和排除标准筛选文献及评估文献质量并提取数据。采用REVMAN5.3软件进行荟萃分析。结果最终纳入14篇文献、共843例PPC患者,其中EUS-GD组485例,PD组358例。荟萃分析结果显示,在技术成功率、临床成功率、并发症发生率方面,EUS-GD组与PD组的差异均无统计学意义(OR=0.69,95%CI 0.32~1.46;OR=1.31,95%CI 0.88~1.95;OR=1.01,95%CI 0.70~1.47,P值均>0.05);而EUS-GD组的复发率和再干预率显著低于PD组,差异有统计学意义(OR=0.45,95%CI 0.23~0.85;OR=0.51,95%CI 0.28~0.93,P值均<0.05)。结论与PD相比,EUS-GD能显著降低PPC术后复发率和再干预率,治疗PPC更具有优势。Original Article A meta-analysis on the comparison between endoscopic ultrasound-guided drainage and percutaneous drainage for treating pancreatic pseudocyst Li Congxiang,Zhang Yanqing,Zhao Jun,Tian Shuni,Guo Anbing,Lu Lin,Peng Lijun Published 2023-08-20 Cite as Chin J Pancreatol,2023,23(4):283-289.DOI:10.3760/cma.j.cn115667-20220204-00014 Abstract Objective To evaluate the efficacy of endoscopic ultrasound-guided drainage(EUS-GD)and percutaneous drainage(PD)for the treatment of pancreatic pseudocyst(PPC)by meta-analysis.Methods The key words were pancreatic pseudocyst,endoscopic ultrasonography,percutaneous drainage,endoscopic ultrasound-guided,EUS and EUS-guided,and the databases of CNKI,Wanfang,PubMed and Web of science were searched from the establishment to October 1,2021 for the retrospective cohort studies on PD,endoscopic ultrasonography and PPC.The article were screened and the quality was evaluated according to the pre-set inclusion and exclusion criteria;and important data were extracted.The software REVMAN5.3 was used for meta-analysis.Results 14 articles were finally included,and a total of 843 patients with PPC were enrolled(485 in the EUS-GD group and 358 in the PD group).Mesh meta-analysis showed that in the incidence of technical success rate,clinical success rate and complication rate,there were no significant differences between PD group and EUS-GD group(OR=0.69,95%CI 0.32-1.46;OR=1.31,95%CI 0.88-1.95;OR=1.01,95%CI 0.70-1.47,all P value>0.05);but the incidence of the recurrence rate and reintervention rate in EUS-GD group were significantly lower than those in the PD group and the differences were statistically significant(OR=0.45,95%CI 0.23-0.85;OR=0.51,95%CI 0.28-0.93,all P value<0.05).Conclusions Compared with PD,EUS-GD can significantly reduce recurrence rate and complication rate,and it has more advantages than PD for the treatment of PPC.

关 键 词：胰腺假性囊肿 超声内镜 引流术 Meta分析 

分 类 号：R576[医药卫生—消化系统]