1990—2019年全球肿瘤发病死亡分析  

Analysis of global cancer incidence and mortality from 1990 to 2019

作　　者：赵倩雯 彭丹莉 秦韬[1] 毛国飞 唐辉[1] 杨峻[1] Zhao Qianwen;Peng Danli;Qin Tao;Mao Guofei;Tang Hui;Yang Jun(Department of Clinical Laboratory,Affiliated Hospital of Guilin Medical University,Guilin 541001,China)

机构地区：[1]桂林医学院附属医院检验科,桂林541001

出　　处：《国际肿瘤学杂志》2023年第7期425-431,共7页Journal of International Oncology

摘　　要：目的分析1990—2019年全球肿瘤发病死亡情况。方法利用全球疾病负担研究2019(GBD2019)数据库,分析1990—2019年全球肿瘤发病死亡情况、肿瘤发病死亡顺位、不同年龄组发病死亡情况以及发病死亡趋势。通过世界标准人口年龄结构进行标化,获得标化发病率和标化死亡率。结果1990年,全球肿瘤发病例数为1029.59万,发病率为192.45/10万,死亡例数为573.26万,死亡率为107.16/10万;2019年,全球肿瘤发病例数为2356.85万,发病率为304.60/10万,死亡例数为1002.28万,死亡率为129.54/10万,均较1990年升高。2019年,男女合计全球发病率最高的肿瘤为肺癌(29.21/10万),第2~5位依次为结直肠癌、乳腺癌、前列腺癌和胃癌,其中男性发病率最高为肺癌(39.24/10万)、女性为乳腺癌(51.27/10万);男女合计全球死亡率最高的肿瘤为肺癌(26.40/10万),第2~5位依次为结直肠癌、胃癌、乳腺癌和胰腺癌,其中男性死亡率最高的为肺癌(35.72/10万)、女性为乳腺癌(17.85/10万)。2019年,全球肿瘤发病率随年龄的增长呈上升趋势,在25岁前发病率较低,25岁之后发病率升高较快,男女合计、男性和女性发病率均在85岁以上年龄组达到高峰,分别为3084.18/10万、4434.81/10万和2353.07/10万;20~50岁年龄组女性发病率高于男性,55岁以上年龄组男性发病率高于女性;2019年男女合计在20岁以上、男性在55岁以上、女性在15岁以上年龄组发病率均高于1990年相应年龄组发病率。2019年,全球肿瘤死亡率随年龄的增长呈上升趋势,在35岁前死亡率较低,35岁之后死亡率升高较快,男女合计、男性和女性死亡率均在85岁以上年龄组达到高峰,分别为1787.84/10万、2509.87/10万和1369.99/10万;20~40岁年龄组女性死亡率高于男性,45岁以上年龄组男性死亡率高于女性;2019年男女合计、男性和女性在0~80岁死亡率均低于1990年,2019年85岁以上年龄组死亡率高于1990年。全球肿瘤标化发�Objective To analyze the global incidence and mortality of cancer from 1990 to 2019.Methods The Global Burden of Disease Study 2019(GBD2019)database was utilized to analyze the global incidence and mortality of cancer,the order of incidence and mortality of cancer,the incidence and mortality of different age groups,and the trend of incidence and mortality from 1990 to 2019.Standardized incidence and mortality rates were derived by utilizing the world standard population age structure.Results In 1990,global cancer cases numbered 10.2959 million with an incidence rate of 192.45/100000,leading to 5.7326 million deaths and a mortality rate of 107.16/100000.While in 2019,global cancer cases escalated to 23.5685 million with an incidence rate of 304.60/100000,resulting in 10.0228 million deaths and a mortality rate of 129.54/100000,all higher than those in 1990.In 2019,lung cancer showed the highest incidence rate of both sexes gastric cancer.The incidence of lung cancer was highest among males(39.24/100000),while the incidence of breast cancer was highest among females(51.27/100000).Lung cancer also had the highest mortality rate worldwide in both sexes combined(26.40/100000),followed by colorectal cancer,gastric cancer,breast cancer and pancreatic cancer.Lung cancer had the highest mortality among males(35.72/100000),while breast cancer had the highest mortality among females(17.85/100000).In 2019,the global cancer incidence rate showed an upward trend with age.The incidence rate was low before the age of 25,and increased rapidly after the age of 25.The incidence rates of both sexes combined,males and females all reached the peak in the age group of over 85 years old,which were 3084.18/100000,4434.81/100000 and 2353.07/100000 respectively;The incidence rate of females in the age group of 20-50 years old was higher than that of males,but the incidence rate of males in the age group of over 55 years old was higher than that of females.Compared with 1990,the incidence rates of both sexes combined in the age group of ove

关 键 词：肿瘤 全球疾病负担 发病率 死亡率 

分 类 号：R73-31[医药卫生—肿瘤]