口腔颌面部肌纤维瘤7例临床病理分析  

Myofibroma of the oral and maxillofacial region:a clinicopathological analysis of 7 cases

作　　者：陈峰 王芳 陈新明 刘克 CHEN Feng;WANG Fang;CHEN Xin-ming;LIU Ke(MY Dental Cinlic,Hubei Wuhan 430021,China;Hospital of Stomatology,Wuhan University,Hubei Wuhan 430079,China)

机构地区：[1]武汉萌芽齿科门诊部,湖北武汉430021 [2]武汉大学口腔医院,湖北武汉430079

出　　处：《临床口腔医学杂志》2023年第8期472-475,共4页Journal of Clinical Stomatology

摘　　要：目的:总结口腔颌面部肌纤维瘤的临床病理特点。方法:收集7例口腔颌面部肌纤维瘤病例,分析其临床资料,复习组织学和免疫组化染色特点。结果:7例中男性5例,女性2例;患者年龄2个月~23岁,平均年龄和中位年龄分别为12岁和10岁。7例均为单发病损,其中发生于下颌骨内3例,下颌牙龈2例,腮腺区和颞肌各1例。光镜下肿瘤显示双相性形态特征,免疫组化标记α-SMA弥漫阳性。7例均行手术切除,随访时间8~73个月均未见复发。结论:口腔颌面部肌纤维瘤好发于儿童和青少年,局部病灶切除或颌骨病灶刮治后预后良好。正确认识其临床、影像学、病理学特点有助于减少误诊。Objective:To summarize the the clinicopathologic features of myofibroma in the oral and maxillofacial region.Methods:The clinical data,histopathological features,and immunohistochemical profiles of 7 cases of myofibroma in the oral and maxillofacial region were retrospectively analyzed.Results:Out of the 7 cases,5 were male and 2 were female.The age of diagnosis ranged from 2 months to 23 years of age(mean 12 years,median 10 years).All 7 cases were solitary,3 occurred in the mandible,2 in the mandibular gingiva,1 in the soft tissue of parotid region and 1 in the temporal muscle region.Microscopic examination showed a biphasic pattern.Immunohistochemically,the tumor cells were diffusely positive for α-SMA.All 7 lesions were surgical excised.Follow-up time ranged from 8 to 73 months,and none recurred.Conclusion:Myofibromas of the oral and maxillofacial region occurs predominantly in children and adolescents.It can be treated by local excision or curettage with favourable prognosis.Correct recognition of the clinical,radiologic and histologic features of this tumor is helpful to avoid misdiagnosis.

关 键 词：肌纤维瘤 肌纤维瘤病 口腔颌面部 临床病理 

分 类 号：R739.87[医药卫生—肿瘤]