脑桥中央髓鞘溶解症的临床随访观察  

Clinical follow-up observation of central pontine myelinolysis

作　　者：张丽丽[1,2] 丁岩 卫华[1] Zhang Lili;Ding Yan;Wei Hua(Department of Neurology,Xuanwu Hospital,Capital Medical University,Beijing 100053,China)

机构地区：[1]首都医科大学宣武医院神经内科,北京100053 [2]河北省唐山市开滦总医院神经内科

出　　处：《北京医学》2023年第6期529-532,共4页Beijing Medical Journal

摘　　要：目的 探讨脑桥中央髓鞘溶解症(central pontine myelinolysis,CPM)的临床特征、影像学特点及其变化和预后。方法 回顾性分析首都医科大学宣武医院收治的1例CPM患者随访前后的临床、影像学和预后资料。结果 本例患者男性,41岁,以吞咽困难、肢体瘫痪为临床表现,MRI表现为典型的脑桥中央部异常信号、T1WI低信号、T2WI高信号、DWI高信号,FLAIR高信号。出院后第2个月、第8个月随访,患者无明显临床症状;出院后12个月随访,MRI结果提示脑干未见异常信号影。结论 CPM患者临床症状消失早,但MRI改变可持续约1年。Objective To explore the clinical and imaging features,changes and prognosis of central pontine myelinolysis(CPM).Methods The clinical,imaging and prognosis data before and after follow-up of a CPM patient admitted to Xuanwu Hospital,Capital Medical University were analyzed.Results The patient was a 41-year-old male,presented with dysphagia and limb paralysis as clinical manifestations.MRI showed typical abnormal signals in the central pontine,low signal intensity on T1WI,high signal intensity on T2WI,high signal intensity on DWI,and high signal intensity on FlAIR.The patient had no obvious clinical symptoms at the two and eight months follow-up after discharge.MRI results showed no abnormal signal shadow in brain stem at 12 months follow-up after discharge.Conclusions The clinical symptoms of CPM patients disappeared early,but the MRI changes can last about one year.

关 键 词：脑桥中央髓鞘溶解症 临床症状 影像学 随访 

分 类 号：R744.5[医药卫生—神经病学与精神病学]