α-Chymotrypsin-Catalyzed Synthesis of Bis(indolyl)alkanes in Water  

作　　者：Dazhao Sun Guofang Jiang Zongbo Xie Zhanggao Le 

机构地区：[1]Department of Applied Chemistry,East China Institute of Technology,Nanchang,Jiangxi 330013,China

出　　处：《Chinese Journal of Chemistry》2015年第4期409-412,共4页中国化学（英文版）

基　　金：support of the National Natural Science Foundation of China(Nos.21262002,21462001 and 21465002);the Natural Sci-ence Foundation of Jiangxi(Nos.20122BAB203006,20142BAB203008);the Science and Technology Foun-dation of the Jiangxi Education Department(Nos.KJLD12006,GJJ13468,GJJ14466 and KJLD14050).

摘　　要：A novel methodology for the synthesis of bis(indolyl)methanes by the reaction of aromatic aldehydes and indole in water has been developed,and a series of desired products were obtained in moderate to excellent yields(from 65%to 97%)using 1.2 mg/mLα-chymotrypsin as biocatalyst.

关 键 词：bis(indolyl)methanes Α-CHYMOTRYPSIN WATER BIOCATALYSIS tandem reaction 

分 类 号：O62[理学—有机化学]