An Environmentally Benign Catalytic Method for Versatile Synthesis of 1,4-Dihydropyridines via Multicomponent Reactions  

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作  者:Shuo Cao Shanshan Zhong Changfeng Hu Jie-Ping Wan Chengping Wen 

机构地区:[1]Key Laboratory of Functional Small Organic Molecule,Ministry of Education,College of Chemistry and Chemical Engineering,Jiangxi Normal University,Nanchang,Jiangxi 330022,China [2]College of Basic Medical Sciences,Zhejiang Chinese Medical University,Hangzhou,Zhejiang 310053,China

出  处:《Chinese Journal of Chemistry》2015年第5期568-572,共5页中国化学(英文版)

基  金:the Department of Education of Jiangxi Province(No.GJJ13245);the Open Research Project from College of Basic Medical Sciences,Zhejiang Chinese Medical University and a Innovative Program of Graduate Students of Jiangxi Province(No.YC2014-S158).

摘  要:The synthesis of diverse 1,4-dihydropyridines have been achieved via the multicomponent reactions of aldehydes,enaminones and amines.The reactions have been smoothly performed in water to provide all products with moderate to excellent yields by using lactic acid as a green catalyst.

关 键 词:lactic acid catalysis multicomponent reactions 1 4-dihydropyridines green catalysis HETEROCYCLE 

分 类 号:O62[理学—有机化学]

 

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