Synchronous rectal adenocarcinoma and intestinal mantle cell lymphoma:A case report  

作　　者：Kim-Van Vu Nguyen-Van Trong Nguyen-Thi Khuyen Do Huyen Nga Hoang Anh Nguyen Tien Trung PhamTrung Thong Nguyen Minh Duc 

机构地区：[1]Department of General Surgery,Vietnam National Cancer Hospital,Ha Noi 100000,Viet Nam [2]Department of Practical Surgery,Hanoi Medical University,Ha Noi 100000,Viet Nam [3]Department of Oncology,Hanoi Medical University,Ha Noi 100000,Viet Nam [4]Pathology and Molecular Biology Center,Vietnam National Cancer Hospital,Ha Noi 100000,Viet Nam [5]Department of Hematologic Oncology,Vietnam National Cancer Hospital,Ha Noi 100000,Viet Nam [6]Department of Radiology,Pham Ngoc Thach University of Medicine,Ho Chi Minh City 700000,Viet Nam

出　　处：《World Journal of Clinical Cases》2023年第24期5772-5779,共8页世界临床病例杂志

摘　　要：BACKGROUND Mantle cell lymphoma(MCL)of the gastrointestinal tract is a rare malignancy,accounting for about 0.2%of malignant colorectal tumors.MCL synchronous with rectal adenocarcinoma is extremely rare.We know of only a few cases reported in the literature.We describe the case of a patient with synchronous rectal adenocarcinoma and intestinal MCL.CASE SUMMARY A 63-year-old man was admitted to our hospital due to abdominal pain and hematochezia over the past month.The patient was diagnosed with middle rectal cancer cT2N0M0 and underwent surgery.However,we found a large tumor in the small intestine during surgery.The patient underwent total mesorectal excision for rectal cancer and resectioning of the ileal segment containing the large mass.Pathology and immunohistochemistry revealed the presence of both rectal adenocarcinoma and pathognomonic MCL stage IIE presenting as multiple lymphomatous polyposis.The patient subsequently underwent RDHAP/RCHOP chemotherapy and was maintained with rituximab.A Positron Emission Tomography and Computed Tomography(PET/CT)scan showed that the disease responded well to treatment without tumor-increased metabolism in the gastrointestinal tract.CONCLUSION Synchronous rectal adenocarcinoma and intestinal MCL presenting as multiple lymphomatous polyposis are extremely rare.MCL is often discovered fortuitously when rectal cancer is diagnosed.The coexistence of these tumors poses treatment challenges.

关 键 词：Mantle cell lymphoma Multiple lymphomatous polyposis Rectal adenocarcinoma SYNCHRONOUS Gastrointestinal tract Case report 

分 类 号：R734.1[医药卫生—肿瘤]