Risk factors for stroke recurrence in young patients with first-ever ischemic stroke:A meta-analysis  

作　　者：Yu Xia Han Liu Rui Zhu 

机构地区：[1]Department of Neurology,The Third People’s Hospital of Hefei(The Third Clinical College of Anhui Medical University),Hefei 230022,Anhui Province,China [2]Department of Neurology,The First Affiliated Hospital of Anhui Medical University(Anhui Public Health Clinical Center),Hefei 230041,Anhui Province,China

出　　处：《World Journal of Clinical Cases》2023年第26期6122-6131,共10页世界临床病例杂志

基　　金：The Key Research Project of The Third People's Hospital of Hefei,No.SYKZ202301.

摘　　要：BACKGROUND At present,the incidence rate of ischemic stroke in young people is increasing yearly,and the age of onset is increasingly young.Therefore,primary and secondary prevention of ischemic stroke in young people,especially secondary prevention,is particularly crucial.AIM We aimed to comprehensively evaluate risk factors for stroke recurrence in firstever young ischemic stroke(YIS)patients.METHODS The meta-analysis was used to quantitatively analyze the research results on risk factors for stroke recurrence in first-ever YIS patients both domestically and internationally.Stata12.0 software was used for heterogeneity testing,publication bias analysis,sensitivity analysis,and the calculation of combined odds ratios and 95%confidence intervals.RESULTS The odds ratio(OR)values of the relationship between hypertension and hyperlipidemia and recurrence of first-ever YIS were 1.54(1.05-2.26)and 1.12(1.00-1.25),respectively.The OR values of male sex,type 2 diabetes,smoking,drinking and YIS recurrence were 1.66(0.98-2.79),1.01(0.64-1.59),1.21(0.83-1.76),and 1.28(0.82-2.53),respectively.The relationship between male sex,type 2 diabetes,smoking,drinking and YIS recurrence was ambiguous.CONCLUSION Hypertension and hyperlipidemia are important risk factors for stroke recurrence in first-ever YIS patients,and active intervention should be taken.

关 键 词：Young ischemic stroke First-ever Risk factors RECURRENCE META-ANALYSIS 

分 类 号：R743[医药卫生—神经病学与精神病学]