传染性疾病专科医院眼科手术患者术前血清传染性标志物检测结果分析  

Analysis of preoperative serum infectious disease marker testing in patients undergoing ophthalmic surgery at an infectious disease hospital

作　　者：阮方 孔文君 张薇[1] 谢连永[1] 董宏伟[1] RUAN Fang;KONG Wen-jun;ZHANG Wei(Department of Ophthalmology,Beijing Youan Hospital,Capital Medical University,Beijing Infectious Eye Disease Diagnosis and Treatment Center,Beijing 100069,China)

机构地区：[1]首都医科大学附属北京佑安医院,北京市感染性眼病诊疗中心,北京100069

出　　处：《临床和实验医学杂志》2023年第16期1784-1787,共4页Journal of Clinical and Experimental Medicine

摘　　要：目的探讨北京一家传染性疾病专科医院眼科手术患者血清传染性疾病标志物检测的结果及特征。方法回顾性分析2019年1月至2021年12月于首都医科大学附属北京佑安医院住院行眼科手术的患者术前感染筛查结果,所有患者均常规静脉抽血,统一行乙型肝炎病毒表面抗原(HBsAg)、丙型肝炎病毒抗体(抗-HCV)、梅毒螺旋体抗体(抗-TP)及人类免疫缺陷病毒抗体(抗-HIV)检测并记录性别、年龄等人口学资料。结果共纳入854例患者,其中282例至少有1项传染性疾病指标血清学阳性,阳性率为33.02%;男性208例(73.76%),女性74例(26.24%);年龄(54.87±11.69)岁,≤40岁76例,41~60岁87例,≥61岁119例;血清HIV阳性率为18.15%,TP阳性率为6.09%,HBV阳性率8.08%,HCV阳性率2.58%。16例(1.87%)患者合并两种传染性疾病,均为HIV合并TP。17例(1.99%)患者因眼科术前筛查首次发现传染性指标阳性。抗-HIV阳性患者的年龄较阴性降低,HBVsAg阳性、抗-HCV阳性患者年龄较阴性升高,差异均有统计学意义(P<0.05)。抗-HIV阳性男性患者比率高于阴性,差异有统计学意义(P<0.05)。结论传染性疾病专科医院眼科术前传染性疾病标志物检测以抗-HIV阳性为主,多重感染主要为HIV合并TP,偶发阳性现象存在,不同传染性疾病存在不同年龄及性别特征,眼科相关医务人员应加强对相关疾病的认识及筛查意识,以提高医疗保障水平。Objective To investigate the results and characteristics of serum infectious disease marker testing in patients undergoing ophthalmic surgery at an infectious disease hospital in Beijing.Methods A retrospective cross-sectional study was conducted on patients who were admitted to Beijing Youan Hospital,Capital Medical University for ophthalmic surgery from January 2019 to December 2021.All patients were tested for hepatitis B virus surface antigen(HBsAg),hepatitis C virus antibodies(anti-HCV),syphilis spirochetes antibodies(anti-TP),and human immunodeficiency virus antibodies(anti-HIV),and demographic data such as gender and age were also recorded.Results A total of 854 patients were included,of which 282 had at least one infectious disease indicator serologically positive,with a 33.02%positivity rate,208 males(73.76%)and 74 females(26.24%);age(54.87±11.69)years old,76 cases≤40 years old,87 cases 41-60 years old,119 cases≥61 years old;18.15%for HIV,6.09%for TP,8.08%for HBV,and 2.58%for HCV.Sixteen patients(1.87%)had a combination of two infectious diseases,all of which were HIV combined with TP.Seventeen patients(1.99%)were first found positive for infectious indicators due to preoperative ophthalmic screening.The age of anti-HIV positive patients decreased compared to negative,while the age of HBVsAg positive and anti-HCV positive patients increased compared to negative,the differences were statistically significant(P<0.05).The proportion of male patients with anti-HIV positivity was higher than that with negative results,and the difference was statistically significant(P<0.05).Conclusion Preoperative infectious disease marker testing in ophthalmology of infectious disease hospitals is mainly anti-HIV positive,multiple infections mostly for HIV combined with TP,the occasional positive exists,and different infectious diseases exist with different age and gender characteristics,which all suggest that ophthalmology-related medical staff should strengthen the screening awareness to improve the level of medical p

关 键 词：肝炎 乙型 肝炎 丙型 梅毒 传染性疾病 眼科手术 艾滋病 

分 类 号：R779.6[医药卫生—眼科]