熊胆开窍汤治疗邪热内陷心包,痰热壅闭清窍型急性脑中风的临床观察  

Acute Stroke(Evil Heat Invaginating Pericardium,Phlegm Heat Obstruction)

作　　者：吴春洪[1] 廖丽媛 陈文参 陈均艺 卢晓波 吴炜添 许成勇[1] 卢永兵[1] WU Chunhong;LIAO Liyuan;CHEN Wenshen;CHEN Junyi;LU Xiaobo;WU Weitian;XU Chengyong;LU Yongbing(Jieyang Hospital of Traditional Chinese Medicine,Jieyang 522000,Guangdong,China)

机构地区：[1]揭阳市中医院,广东揭阳522000

出　　处：《辽宁中医杂志》2023年第8期93-96,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：广东省中医药局科研项目(20201414)。

摘　　要：目的观察熊胆开窍汤治疗邪热内陷心包,痰热壅闭清窍型急性脑中风的临床疗效。方法选取该院2020年1月—2021年12月收治的60例急性脑中风患者,依照随机投掷法分组,对照组(西医治疗)30例、试验组(西医治疗+熊胆开窍汤口服),对比两组症状改善、神经功能缺损评分、不良反应发生率、临床疗效。结果试验组总有效率为92.31%(24/26),高于对照组的68.00%(17/25),差异有统计学意义(P<0.05);试验组的中医证候疗效为96.15%(25/26),高于对照组的60.00%(15/25),差异有统计学意义(P<0.05);治疗前两组主要症状差异无统计学意义(P>0.05);治疗后两组症状均有所改善,与组内治疗前比较,差异有统计学意义(P<0.05),但治疗后组间无较大差异无统计学意义(P>0.05);治疗前两组神经功能缺损评分差异无统计学意义(P>0.05);试验组治疗后NIHSS评分低于对照组,差异有统计学意义(P<0.05)。两组均未出现明显不良反应。结论熊胆开窍汤在急性脑中风疾病治疗中可显著提高神经功能,改善语言、肢体功能,减轻临床症状,均无不良反应,疗效确切,值得推广。Objective To observe the clinical effect of Xiongdan Kaiqiao Decoction on the treatment of evil heat entrapment pericardium,phlegm heat obstructing Qingqiao type acute cerebral stroke.Methods Sixty patients with acute cerebral apoplexy admitted to our hospital from January 2020 to December 2021 were divided into two groups by random throwing method,30 patients in control group(Western medicine treatment)and 30 patients in experimental group(Western medicine treatment+oral Xiongdan Kaiqiao Decoction).Symptom improvement,neurological deficit score,incidence of adverse reactions and clinical efficacy of the two groups were compared.Results The total effective rate of experimental group was 92.31%(24/26),which was higher than that of control group(68.00%(17/25),and the difference was statistically significant(P<0.05).The curative effect of TCM syndrome in experimental group was 96.15%(25/26),which was higher than that in control(60.00%(15/25),and the difference was significant(P<0.05).Before treatment,there was no significant difference in the main symptoms between the two groups(P>0.05).After treatment,symptoms of both groups were improved,and the difference was significant compared with before treatment(P<0.05),but there was no significant difference between the two groups after treatment(P>0.05).Before treatment,there was no significant difference in neurological deficit scores between the two groups(P>0.05).The NIHSS score of experimental group was lower than that of control group after treatment,and the difference was significant(P<0.05).There were no obvious adverse reactions in both groups.Conclusion Xiongdan Kaiqiao Decoction can significantly improve nerve function,improve language and limb function,and alleviate clinical symptoms in the treatment of acute cerebral apostrophy.There are no adverse reactions.

关 键 词：急性脑中风 熊胆开窍汤 神经功能缺损评分 中医证候 

分 类 号：R743.3[医药卫生—神经病学与精神病学]