磁共振动态增强扫描及信号强度-时间曲线在前列腺良恶性病变中的诊断价值  

Diagnostic value of dynamic contrast-enhanced magnetic resonance imaging and signal intensity-time curve in benign and malignant prostate lesions

作　　者：岳孟超 刘阳 谢瑛 YUE Mengchao;LIU Yang;XIE Ying(Department of Radiology,Bazhong Central Hospital in Sichuan Province,Bazhong,Sichuan,636000)

机构地区：[1]四川省巴中市中心医院放射科,四川巴中636000

出　　处：《实用临床医药杂志》2023年第15期82-85,共4页Journal of Clinical Medicine in Practice

基　　金：四川省医学科研青年创新课题(Q15010)。

摘　　要：目的 探讨磁共振动态增强扫描(DCE-MRI)及信号强度-时间曲线(SI-T曲线)对前列腺良恶性病变的诊断价值。方法 选取102例前列腺疾病患者为研究对象,并分为良性组65例和恶性组37例。采用受试者工作特征(ROC)曲线分析DCE-MRI、SI-T检测及二者联合检测对前列腺良恶性病变的诊断价值。结果 恶性组患者的容量转移常数(Ktrans)、速率常数(Kep)、血管外细胞外间隙容积比(Ve)大于良性组,差异有统计学意义(P<0.05)。恶性组患者的SI-T曲线速升缓降型占比高于良性组,持续缓升型、缓升平台型占比低于良性组,差异有统计学意义(P<0.05)。恶性组患者的达峰时间短于良性组,强化程度、强化率高于良性组,差异有统计学意义(P<0.05);DCE-MRI指标及SI-T曲线参数联合检测诊断前列腺良恶性病变的曲线下面积(AUC)大于DCE-MRI指标、SI-T曲线参数单独检测,差异有统计学意义(P<0.05)。结论 DCE-MRI、SI-T曲线参数联合检测在前列腺良恶性病变中具有较好的诊断价值。Objective To explore the diagnostic value of dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI)and signal intensity-time(SI-T)curve in benign and malignant prostate lesions.Methods A total of 102 patients with prostate disease were selected as the study objects,and were divided into benign group(65 cases)and malignant group(37 cases).Receiver operating characteristic(ROC)curve was used to analyze the diagnostic value of DCE-MRI,SI-T alone and their combined detection in benign and malignant prostate lesions.Results The volume transfer constant(Ktrans),rate constant(Kep)and extravascular extracellular space volume fraction(Ve)of patients in the malignant group were higher than those in the benign group(P<0.05).The proportion of fast growth and slow decline of SI-T curve in the malignant group was significantly higher than that in the benign group,and the proportion of continuous slow rise and slow rise platform type was significantly lower than that in the benign group(P<0.05).The peak time of the malignant group was significantly shorter than that of the benign group,and the degree and rate of reinforcement were significantly higher than those of the benign group(P<0.05).The area under the curve(AUC)of the combined detection of DCE-MRI or SI-T curve parameter in the diagnosis of benign and malignant prostate lesions was greater than that of the single detection of DCE-MRI or SI-T curve parameter(P<0.05).Conclusion The combined detection of DCE-MRI and SI-T curve has good diagnostic value in diagnosis of benign and malignant prostate lesions.

关 键 词：磁共振动态增强扫描 信号强度-时间曲线 前列腺良恶性病变 容量转移常数 

分 类 号：R737.25[医药卫生—肿瘤] R445.2[医药卫生—临床医学]