放射治疗在小细胞肺癌卵巢转移中的应用价值  

Perspective of radiotherapy for ovarian metastasis from small cell lung cancer

作　　者：封赵德 曲以平 孙玄子 任娟[1] 张晓智[1] 杨蕴一[1] FENG Zhaode;QU Yiping;SUN Xuanzi;REN Juan;ZHANG Xiaozhi;YANG Yunyi(Department of Oncology and Radiotherapy,The First Affiliated Hospital of Xi’an Jiaotong University,Xi’an 710061,China)

机构地区：[1]西安交通大学第一附属医院肿瘤放疗科,陕西西安710061

出　　处：《西安交通大学学报（医学版）》2023年第4期557-562,共6页Journal of Xi’an Jiaotong University（Medical Sciences）

基　　金：陕西省自然科学基金资助项目(No.2020JM-396)。

摘　　要：目的探讨放射治疗在小细胞肺癌卵巢转移中的治疗价值。方法回顾报道2例小细胞肺癌卵巢转移进行放射治疗的患者资料,并结合文献报道分析在小细胞肺癌卵巢转移治疗中介入放射治疗的价值。结果2例患者卵巢转移灶经局部放疗均得到持续控制,其中一例完全缓解,局部PFS已达到21月,目前仍处于持续缓解中,较既往文献报道的小细胞肺癌卵巢转移的病例生存期明显延长。结论尽管小细胞肺癌卵巢转移的预后仍然很差,放疗可能是改善这些患者生存时间的系统治疗策略之一。Objective To evaluate the therapeutic value of radiotherapy for ovarian metastasis from small cell lung cancer.Methods Two patients with ovarian metastasis from small cell lung cancer were recruited,and the value of radiotherapy in the system treatment strategies was analyzed combined with literature reports.Results The two patients both benefited from local radiotherapy plus system treatment.One was still in complete remission,and compared to that reported in the literature,the local PFS improved to 21 months.Conclusion Although the prognosis of small cell lung cancer with ovarian metastasis is still poor,radiotherapy might be one of the systematic treatment strategies for improving the survival time of these patients.

关 键 词：卵巢转移癌 小细胞肺癌 放射治疗 预后 

分 类 号：R734.2[医药卫生—肿瘤] R815[医药卫生—临床医学]