光生物调节治疗阿尔茨海默病研究进展  

Research progressofphotobiomodulation for Alzheimer's disease

作　　者：徐国栋[1] 吕泽平 汪待发[4] 郭蓉 XU Guodong;LV Zeping;WANG Daifa;GUO Rong(Department of Infectious Disease,The People's Hospital of Danyang,Affiliated Danyang Hospital of Nantong University,Danyang 212300,China;Rehabilitation Hospital Affiliated to National Research Center for Rehabilitation Assistive Devices,Beijing 100176,China;Beijing Key Laboratory of Assistive Technology for Rehabilitation of Elderly Dysfunction,Beijing 100176,China;School of Biological Science and Medical Engineering,Beihang University,Beijing 100083,China)

机构地区：[1]江苏省丹阳市人民医院,丹阳212300 [2]国家康复辅具研究中心附属康复医院,北京100176 [3]北京市老年人功能障碍康复辅助技术重点实验室,北京100176 [4]北京航空航天大学生物与医学工程学院,北京100083

出　　处：《科技导报》2023年第15期79-88,共10页Science & Technology Review

基　　金：国家重点研发计划项目(2018YFC2001700,2020YFC2004200);国家重大科研仪器研制项目(81927804);江苏省重点研发计划项目(BE2021077);。

摘　　要：阿尔茨海默病(AD)是一种以进行性记忆丧失和认知功能障碍为特征的神经退行性疾病。光生物调节(PBM)是一种针对AD治疗的有前景的创新技术路线。介绍了PBM对AD的作用机制以及相关的动物实验和临床研究,分析了PBM对AD治疗的可行性、有效性、研究重点和难点,总结了PBM应用于AD治疗的研究趋势。Alzheimer's disease(AD)is a neurodegenerative disease with progressive memory loss and cognitive impairment.Photobiomodulation(PBM)is a promising and innovative therapy for AD treatment.This article reviews the mechanisms of action of PBM for AD treatment and related animal experiments and clinical studies,then analyzes the feasibility,effectiveness,research priorities and challenges of PBM for AD treatment,and finally summarizes the future research trends of PBM for AD treatment,so as to provide a reference for follow-up research.

关 键 词：阿尔茨海默病 光生物调节 无创治疗 

分 类 号：R749.16[医药卫生—神经病学与精神病学]