头颅磁共振成像对早产儿脑损伤患儿神经发育异常早期诊断价值  

Early diagnostic value of cranial MRI for neurodevelopmental abnormalities in premature infants with brain injury

作　　者：牛巍巍 Niu Weiwei(Department of Medical Imaging,Jiaozuo Maternal and Child Health Hospital,Henan 454000,China)

机构地区：[1]河南省焦作市妇幼保健院医学影像科,454000

出　　处：《实用医学影像杂志》2023年第3期197-200,共4页Journal of Practical Medical Imaging

摘　　要：目的探讨头颅磁共振成像对早产儿脑损伤(BIPI)患儿神经发育异常的早期诊断价值。方法选取2020年2月至2022年2月在我院产科出生的60例早产儿作为本次研究对象,在矫正胎龄至40周且各功能区域较稳定时进行头颅MRI检查,按影像学诊断结果分为BIPI组(33例)、非BIPI组(27例)。对比2组MRI神经发育总体成熟度评分(TMS),并观察BIPI组患儿不同部位脑损伤情况及头颅MRI的诊断准确率,待患儿矫正胎龄至3个月,以盖泽尔智能发育诊断系统(GDDS)对2组神经发育状况进行评估。结果BIPI组MRI神经发育成熟度TMS评分较非BIPI组低,差异有统计学意义(P<0.05)。BIPI患儿常见脑损伤部位依次为蛛网膜下腔、脑白质及皮质层等。BIPI组Gesell发育量表评分≥90分患儿占比较非BIPI组低,差异有统计学意义(P<0.05)。神经发育正常患儿TMS评分较神经发育异常患儿更高,差异有统计学意义(P<0.05)。头颅MRI对BIPI的诊断准确率为97%。结论头颅MRI可早期诊断BIPI患儿神经发育异常状况,为临床诊治工作提供参考,值得进一步推广应用。Objective To investigate the value of cranial MRI in the early diagnosis of neurodevelopmental abnormalities in children with brain injury in preterm infants(BIPI).Methods Sixty premature infants who were born in the obstetrics department of our hospital from February 2020 to February 2022 were selected as the subjects of this study.Cranial MRI was performed when the corrected gestational age was 40 weeks and each functional region was stable.They were divided into the BIPI group(n=33)and the non-BIPI group(n=27)according to the imaging diagnosis results.The TMS score of MRI neurodevelopmental maturity was compared between the two groups,and the brain injuries in different parts of the children in the BIPI group and the diagnostic accuracy of head MRI were observed.After the gestational age of the children was corrected to three months,the neurodevelopmental status of the two groups was evaluated with Gajser intelligent development diagnosis system(GDDS).Results The TMS score of MRI neurodevelopmental maturity in the BIPI group was lower than that in the non-BIPI group,and the difference was statistically significant(P<0.05).The common brain injury sites in children with BIPI were subarachnoid space,white matter and cortical layer in sequence.The proportion of children with Gesell score≥90 in the BIPI group was lower than that in the non-BIPI group,and the difference was statistically significant(P<0.05).The TMS score of children with normal neurodevelopment was higher than that of children with abnormal neurodevelopment,and the difference was statistically significant(P<0.05).The diagnostic accuracy of head MRI for BIPI was 96.67%.Conclusion Cranial MRI can provide an early diagnosis of neurodevelopmental abnormalities in children with BIPI,and provide a reference for clinical diagnosis and treatment,which is worthy of further promotion and application.

关 键 词：早产儿 脑损伤 神经发育异常 头颅 磁共振 

分 类 号：R722.6[医药卫生—儿科] R445.2[医药卫生—临床医学]