Study on the clinical effect and safety of Kangfuxin liquid combined with microneedling in the treatment of facial skin photoaging  

作　　者：Yi Chen Hu Ren Qiong Guo Ting-Ting Zhong Rui-Lan Xi Dan Xiao Yan Wang 

机构地区：[1]Department of Dermatology,The Third Hospital of Mianyang(Sichuan Mental Health Center),Mianyang 621000,China [2]Department of Medical Cosmetology,The First Affiliated Hospital of Dali University,Dali 671003,China

出　　处：《Aging Communications》2023年第3期1-5,共5页衰老通讯

摘　　要：Background and Objectives:Microneedling has been introduced as a new technique to address the growing concern of facial skin photoaging.Kangfuxin liquid has been found to promote the process of skin wound repair,including reducing inflammatory response,improving immunity and enhancing antioxidant levels.In this prospective randomized double-blinded study,we wanted to explore the clinical efficacy and safety of Kangfuxin liquid combined with microneedling in treating facial skin photoaging.Methods:57 patients with facial skin photoaging were randomly divided into two groups.The treatment group(28 cases)received microneedle therapy with Kangfuxin liquid,while the control group(29 cases)received microneedle therapy with physiological saline.The treatment interval was 4 weeks,and a total of 3 treatments were performed.Compare the VISIA scores of facial photoaging features such as wrinkles,texture,pores,spots and ultraviolet pigmentation between two groups of patients before and after treatment,Global Score for Photoaging,satisfaction evaluation,and record the occurrence of adverse reactions.Results:After treatment,the treatment group showed more significant improvement in wrinkles,texture,pores,spots and ultraviolet pigmentation,and the Global Score for Photoaging was better than the control group(P<0.05).The satisfaction rate with improving skin in the treatment group was 85.71%,which was higher than 75.86%in the control group(P<0.05).Both groups did not experience adverse reactions such as skin infection,pigmentation or hypopigmentation,scar formation,or worsening of melasma.Conclusion:Kangfuxin liquid combined with microneedling therapy has a good improvement effect on facial skin photoaging,with a low incidence of adverse reactions and high patient satisfaction.It is worthy of clinical promotion.

关 键 词：Kangfuxin liquid microneedling facial skin photoaging VISIA 

分 类 号：R73[医药卫生—肿瘤]