揿针疗法联合中药塌渍在非小细胞肺癌合并中重度癌性疼痛患者中的应用效果  

Application effect of thumbtack needling therapy combined with traditional Chinese medicine collapse stain in patients with non-small cell lung cancer complicated with moderate to severe cancer pain

作　　者：袁丽 孙颖芳 刘华之[3] 刘静 朱志方 潘清华 YUAN Li;SUN Yingfang;LIU Huazhi;LIU Jing;ZHU Zhifang;PAN Qinghua(The Second Department of Internal Medicine,Ganzhou Cancer Hospital,Jiangxi Province,Ganzhou 341000,China;Department of Nursing,Hospital of Gannan Normal University,Jiangxi Province,Ganzhou 341000,China;Department of Public Health,First Affiliated Hospital of Gannan Medical University,Jiangxi Province,Ganzhou 341000,China)

机构地区：[1]江西省赣州市肿瘤医院内二科,江西赣州341000 [2]赣南师范大学医院护理部,江西赣州341000 [3]赣南医学院第一附属医院公共卫生科,江西赣州341000

出　　处：《中国当代医药》2023年第26期50-54,共5页China Modern Medicine

基　　金：江西省卫生健康委科技计划项目(202311994)。

摘　　要：目的探讨揿针疗法联合中药塌渍治疗非小细胞肺癌(NSCLC)合并中重度癌性疼痛患者的临床效果。方法选取2020年1月至2021年9月赣州市肿瘤医院收治的70例NSCLC合并中重度癌性疼痛患者为研究对象,根据随机数字表法将其分为观察组(35例)与对照组(35例)。对照组采用常规西药治疗,观察组在常规西药治疗的基础上增加揿针疗法联合中药塌渍治疗。比较两组患者的镇痛有效率、疼痛评分、生活质量评分、炎症因子水平、不良反应发生率。结果观察组患者镇痛总有效率高于对照组患者,差异有统计学意义(P<0.05)。观察组患者治疗后的视觉模拟评分(VAS)低于对照组,卡氏功能状态评分(KPS)、日常生活活动能力(ADL)评分均高于对照组,差异有统计学意义(P<0.05)。观察组患者治疗后的超敏C反应蛋白(hs-CRP)、Toll样受体4(TLR4)、前列腺素E2(PGE2)水平均低于对照组,差异有统计学意义(P<0.05)。观察组患者治疗期间的不良反应总发生率低于对照组患者,差异有统计学意义(P<0.05)。结论揿针疗法联合中药塌渍治疗NSCLC合并中重度癌性疼痛的效果显著,能够有效缓解患者的疼痛程度,提高患者生活质量,降低炎症因子水平,降低不良反应发生率,可临床推荐。Objective To explore the clinical effect of thumbtack needling therapy combined with traditional Chinese medicine collapse stain on patients with non-small cell lung cancer(NSCLC)complicated with moderate to severe cancer pain.Methods A total of 70 patients with NSCLC complicated with moderate to severe cancer pain admitted to Ganzhou Cancer Hospital from January 2020 to September 2021 were selected as the research objects.According to the random number table method,they were divided into the observation group(35 cases)and the control group(35 cases).The control group was treated with conventional western medicine,and the observation group was treated with thumbtack needling therapy combined with Chinese medicine collapse stain on the basis of conventional western medicine.The analgesic efficiency,pain score,quality of life score,levels of inflammatory factors and incidence of adverse reactions were compared between the two groups.Results The total effective rate of analgesia in the observation group was higher than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the visual analogue scale(VAS)score of the observation group was lower than that of the control group,and the Karnofsky performance status(KPS)and activities of daily living(ADL)scores were higher than those of the control group,and the differences were statistically significant(P<0.05).The levels of high-sensitivity C-reactive protein(hs-CRP),Toll-like receptor 4(TLR4)and prostaglandin E2(PGE2)in the observation group after treatment were lower than those in the control group,and the differences were statistically significant(P<0.05).The total incidence of adverse reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The thumbtack needling therapy combined with traditional Chinese medicine collapse stain has a significant effect on NSCLC patients with moderate to severe cancer pain,which can effectively relieve the

关 键 词：非小细胞肺癌 中重度癌痛 中药塌渍 揿针疗法 临床疗效 

分 类 号：R734.2[医药卫生—肿瘤]