周围组织瓣修复乳房缺损术在早期乳腺癌中的应用效果  

Application effect of peripheral tissue flap in the repair of breast defects in early breast cancer

作　　者：黄蕾润 王耀鹏 黄明锦 赵耀 HUANG Leirun;WANG Yaopeng;HUANG Mingjin;ZHAO Yao(Department of General Surgery,the 926th Hospital of the Joint Logistics Support Force of the People's Liberation Army of China,Yunnan Province,Kaiyuan 661600,China;Department of Burn and Plastic Surgery,the 926th Hospital of the Joint Logistics Support Force of the People's Liberation Army of China,Yunnan Province,Kaiyuan661600,China)

机构地区：[1]中国人民解放军联勤保障部队第926医院普通外科,云南开远661600 [2]中国人民解放军联勤保障部队第926医院烧伤整形科,云南开远661600

出　　处：《中国当代医药》2023年第26期117-120,共4页China Modern Medicine

摘　　要：目的探讨周围组织瓣修复乳房缺损术在早期乳腺癌中的应用效果。方法选取2019年1月至2022年12月中国人民解放军联勤保障部队第926医院收治的60例早期乳腺癌患者作为研究对象,按照随机数字表法分为对照组(30例)与研究组(30例),对照组采用常规保乳术方法,研究组采用保乳术联合周围组织瓣修复乳房缺损术方法。比较两组患者的血清肿瘤标志物水平、乳房美学评分、主观满意度以及术后复发率。结果治疗前,两组患者癌胚抗原(CEA)、糖类抗原153(CA153)和血管内皮生长因子(VEGF)水平比较,差异无统计学意义(P>0.05);治疗后,两组患者CEA、CA153和VEGF水平均低于本组治疗前,且研究组CEA、CA153和VEGF水平均低于对照组,差异有统计学意义(P<0.05)。治疗后,研究组乳房美学评分高于对照组,差异有统计学意义(P<0.05)。治疗后,研究组主观满意度高于对照组,术后复发率低于对照组,差异有统计学意义(P<0.05)。结论早期乳腺癌患者肿瘤整形中,采取周围组织瓣修复乳房缺损术,可在调节患者血清肿瘤标志物水平基础上,改善患者乳房美学评分,提高患者主观满意度,降低术后复发率,临床价值较高。Objective To investigate the application effect of peripheral tissue flap in the repair of breast defects in early breast cancer.Methods A total of 60 patients with early breast cancer admitted to the 926th Hospital of the Joint Logistics Support Force of the People's Liberation Army of China from January 2019 to December 2022 were selected as the research objects,and they were divided into the control group(30 cases)and the study group(30 cases)according to the random number table method.The control group received conventional breast conserving surgery,and the study group received breast conserving surgery combined with peripheral tissue flaps to repair breast defects.The levels of serum tumor markers,breast aesthetic score,subjective satisfaction and postoperative recurrence rate between the two groups were compared.Results Before treatment,there were no statistically significant differences in the levels of carcinoembryonic antigen(CEA),carbohydrate antigen 153(CA153)and vascular endothelial growth factor(VEGF)between the two groups(P>0.05).After treatment,the levels of CEA,CA153 and VEGF in two groups were lower than those before treatment,and the levels of CEA,CA153,and VEGF in the study group were lower than those in the control group,with statistical significances(P<0.05).After treatment,the breast aesthetic score of the study group was higher than that of the control group,with statistically significant difference(P<0.05).After treatment,the subjective satisfaction of the study group was higher than that of the control group,and the postoperative recurrence rate was lower than that of the control group,with statistically significant differences(P<0.05).Conclusion With the application of peripheral tissue flaps in tumor plastic surgery for early breast cancer patients to repair breast defects,the aesthetic score and the subjective satisfaction of patients can be improved,and the recurrence rate after surgery can be reduced on the basis of adjusting the level of tumor markers in patients'serum.The clinical

关 键 词：早期乳腺癌 周围组织瓣修复乳房缺损术 乳房美学评分 血清肿瘤标志物水平 

分 类 号：R737.9[医药卫生—肿瘤]