喉神经内分泌癌的研究进展  

Update on neuroendocrine carcinomas of the larynx

作　　者：余冉(综述) 刘世喜(审校)[1] YU Ran(revieing);LIU Shixi(checking)(Department of Otolaryngology,West China Hospital,Sichuan University,Chengdu 610041,China)

机构地区：[1]四川大学华西医院耳鼻咽喉头颈外科,四川成都610041

出　　处：《西部医学》2023年第9期1400-1404,共5页Medical Journal of West China

基　　金：四川省卫生健康委员会普及应用项目(21PJ022)。

摘　　要：喉癌是头颈部最常见的肿瘤之一,其中以鳞癌居多。而喉原发的神经内分泌癌却十分少见,约占所有喉肿瘤的0.5%。喉神经内分泌癌是一组以神经内分泌分化为特征的恶性异质性上皮性肿瘤,不同亚型的组织病理学、临床表现、治疗及预后差异较大。目前关于喉神经内分泌癌的报道多以单个病例报道为主,缺乏关于此类肿瘤的诊断和治疗方法的指南。本文就喉神经内分泌癌的临床特点、病理诊断、治疗预后等方面的研究进展作一综述,旨在为临床医生提供新的见解,以提高此类肿瘤的诊断效率、治疗效果和患者预后。Laryngeal cancer is one of the most common tumors of the head and neck region,including mostly squamous cell carcinoma.Primary neuroendocrine cancer of laryngeal is rare,accounting for about 0.5%of all laryngeal tumors.Laryngeal neuroendocrine carcinoma is a group of malignant and heterogeneous epithelial tumors characterized by neuroendocrine differentiation,with large differences in the morphology,clinical manifestations,treatment,and prognosis of different subtypes.Current reports on laryngeal neuroendocrine carcinoma are mainly case reports,and guidelines on the diagnosis and treatment of such tumors are lacking.This brief review of the research progress in the clinical features,pathological diagnosis,and therapeutic prognosis of laryngeal neuroendocrine carcinoma,aims to provide clinicians with new and useful insights to improve the diagnostic efficiency,therapeutic efficacy,and patient outcomes of such tumors.

关 键 词：神经内分泌癌 喉癌 免疫组化 预后 综述 

分 类 号：R739.65[医药卫生—肿瘤]