发生在乳腺肌纤维母细胞瘤的临床及影像学表现  

Clinical and Imaging Appearance of Mammary Myofibroblastoma

作　　者：齐修竹 钱雨 刘雅静 周瑾 李娜 陈雅玲 Qi Xiuzhu;Qian Yu;Liu Yajing;Zhou Jin;Li Na;Chen Yaling(Department of Ultrasound,Fudan University Shanghai Cancer Center,Department of Oncology,Shanghai Medical College,Fudan University,Shanghai 200032,China)

机构地区：[1]复旦大学附属肿瘤医院超声诊断科、复旦大学上海医学院肿瘤学系,上海市200032

出　　处：《中国超声医学杂志》2023年第8期950-953,共4页Chinese Journal of Ultrasound in Medicine

基　　金：国家自然科学基金青年基金项目(No.NSFC 82202160);国家自然科学基金青年基金项目(No.NSFC 82001839)。

摘　　要：目的探索发生在乳腺的肌纤维母细胞瘤的临床及影像学表现。方法收集病理诊断为发生在乳腺的肌纤维母细胞瘤患者的临床、影像及病理资料。结果乳腺肌纤维母细胞瘤患者共6例,其中5例女性,1例男性,中位年龄54岁(范围40~62岁)。6例肿块最大直径9~44 mm,5例位于左乳,1例位于右乳,均发生在乳腺外上象限及上方。二维超声上表现为圆形或椭圆形、边界清晰、边缘光整的低回声或等回声肿块;仅1例肿块内见数枚类圆形微小钙化。彩色多普勒超声下仅1例肿块显示边缘条状血流信号。其中3例患者进行乳房乳腺X射线摄影,均显示高或等密度、边界清晰的圆形或椭圆形占位。仅1例患者进行术前MRI检查,显示圆形肿块,边缘清楚,T2WI等信号,增强后明显强化。所有患者均进行肿块切除手术及术后超声检查随访,均未出现复发或转移。结论乳腺肌纤维母细胞瘤在超声、乳腺X射线摄影及MRI检查中,影像表现不具备特异度,术前通过临床及影像学特征较难确定性质,需通过手术切除明确诊断;但其远期预后良好,未出现复发及转移。Objective To explore the clinical and imaging features of mammary myofibroblastomar.Methods The clinical,imaging and pathological data of patients with mammary myofibroblastoma(MFB)pathologically diagnosed were collected.Results There were six cases with MFB,five of whom were female and one was male,with median age 54years(range 40to 62years).The maximum mass diameter of six cases was 9-44mm,five cases were located in the left breast and one case was located in the right breast,all of which occurred in and above the outer upper quadrant and upper quadrant.On two-dimensional ultrasound,it was shown as hypoechioc or isoechoic masses with round or oval shape,well-defined boundary,and circumscribed margin.Calcifications were found in only one case.Blood flow was detected in only one lesion.Three of the patients underwent mammography,all displayed as high or equal density,well-defined,round or oval masses.Only one patient underwent MRI,showed a round mass with clear margin,isostatic signals on T2WI,and significant enhancement.All patients underwent mass excision and postoperative ultrasound follow-up,and there was no recurrence or metastasis.Conclusions The imaging appearance of MFB occurring in the mammary gland is not specific in ultrasonography,mammography and MRI,and it is difficult to diagnose by clinical and imaging characteristics,the diagnosis should be comfirmed by surgical pathology.However,the long-term prognosis of myofibroblastoma is good without recurrence or metastasis.

关 键 词：肌纤维母细胞瘤 乳腺 超声 乳腺X线摄影 MRI 

分 类 号：R737.9[医药卫生—肿瘤]