Sirius Scheimpflug-Placido versus. ultrasound pachymetry for central corneal thickness: meta-analysis  

作　　者：Yili Jin Colm McAlinden Yong Sun Daizong Wen Yiran Wang Jinjin Yu Ke Feng Benhao Song Qinmei Wang Shihao Chen Jinhai Huang 

机构地区：[1]School of Ophthalmology and Optometry and Eye Hospital,Wenzhou Medical University,Wenzhou,Zhejiang,China [2]Department of Ophthalmology,Singleton Hospital,Swansea Bay University Health Board,Swansea,Uk [3]shenzhen Hospital of Integrated Traditional and Western Medicine,Shenzhen,China [4]Key Laboratory of Vision Science,Ministry of Health P.R.China,Wenzhou,Zhejiang,China [5]Eye Hospital of Wenzhou Medical University,270 West Xueyuan Road,Wenzhou 325027,Zhejiang,China.

出　　处：《Eye and Vision》2023年第4期1-11,共11页眼视光学杂志（英文）

基　　金：supported in part by the Foundation of Wenzhou City Science&Technology Bureau(Grant No.Y2020037);Medical and Health Science and Technology Program of Zhejiang Province(Grant No.2019KY111);Zhejiang Provincial&Ministry of Health Research Fund for Medical Sciences(Grant No.WKJ-ZJ-2134);Zhejiang Provincial High-level Talents Program(Grant No.2017-102).

摘　　要：Background:To compare the difference in central corneal thickness(CCT)measurements in normal eyes between a rotating Scheimpflug camera combined with a Placido-disk corneal topographer(Sirius,CSO,Italy)and ultrasound pachymetry(USP).Methods:A systematic literature search was conducted for relevant studies published on PubMed,Medline,EMBASE,and the Cochrane Library and ClinicalTrials.gov from inception to August 1st,2019.Primary outcome measures were CCT measurements between Sirius and USP.A random effects model was used to pool CCT measurements.Results:A total of twelve studies involving 862 eyes were included in this meta-analysis.The meta-analysis found CCT measurements between Sirius and USP to be statistically significantly different(P<0.0001).The mean difference between Sirius and USP was-11.26μm with a 95%confidence interval(CI)(-16.92μm,-5.60μm).The heterogeneity Was IP=60%(P=0.004).Conclusion:CCT measurements with the Sirius Scheimpflug-Placido topographer were statistically significantly lower than USP.However,it may be argued that the mean difference of 11.26μm is not a clinically significant difference.

关 键 词：META-ANALYSIS Central corneal thickness Scheimpflug-Placido topographer Ultrasound pachymetry 

分 类 号：R77[医药卫生—眼科]