放射性碘治疗局部进展期分化型甲状腺癌的价值  

The role of radioiodine in treatment of locally advanced differentiated thyroid cancer

作　　者：林岩松[1] 张腾 LIN Yan-song;ZHANG Teng(Department of Nuclear Medicine,Peking Union Medical College Hospital,Beijing 100730,China;不详)

机构地区：[1]中国医学科学院北京协和医院核医学科,北京100730 [2]首都医科大学附属北京朝阳医院核医学科,北京100120

出　　处：《中国实用外科杂志》2023年第8期876-881,共6页Chinese Journal of Practical Surgery

基　　金：国家重点研发计划“政府间国际科技创新合作/港澳台科技创新合作”重点专项(No.2019YFE0106400);中央高水平医院临床科研业务费项目(No.2022-PUMCH-B-072)。

摘　　要：分化型甲状腺癌(DTC)总体预后良好,死亡风险较低,其管理重点在于防治肿瘤复发及对复发疾病的妥善处理。放射性碘(RAI)作为DTC诊治的重要辅助手段,在复发疾病中发挥着独特的诊疗作用。对局部进展期DTC,RAI的治疗理念、治疗目的、治疗前评估、分子特征与摄碘性的关系等方面研究日益深入,为改善可摄碘的局部进展期病人综合治疗效果,改善病人预后及生活质量提供了更多理论依据。Differentiated thyroid cancer(DTC)generally has a good prognosis and a low risk of death.Thus,the management mainly focuses on the prevention and proper treatment of recurrent diseases.As an important auxiliary method for DTC diagnosis and treatment,radioiodine plays a unique role in recurrent diseases.Recently,along with the increasing of studies on treatment concept,therapeutic purpose,postoperative evaluation,the relationship between molecular characteristics and(radioiodine therapy,RAI)avidity of locally advanced DTC,more theoretical bases have been provided for enhance the comprehensive curative effect and improve patients’prognosis and quality of life.

关 键 词：局部进展期甲状腺癌 分化型甲状腺癌 放射性碘治疗 分子特征 摄碘性 

分 类 号：R736.1[医药卫生—肿瘤]