近视眼与青光眼关系的研究进展  

Research progress on the relationship between myopia and glaucoma

作　　者：朱天翼 刘堃[1] Zhu Tianyi;Liu Kun(Department of Ophthalmology,Shanghai General Hospital,Shanghai Jiao Tong University School of Medicine,National Clinical Research Center for Eye Diseases,Shanghai Key Laboratory of Ocular Fundus Diseases,Shanghai Engineering Center for Visual Science and Photomedicine,Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases,Shanghai 200080,China)

机构地区：[1]上海交通大学医学院附属第一人民医院眼科、国家眼部疾病临床医学研究中心、上海市眼底病重点实验室、上海眼视觉与光医学工程技术研究中心、上海市眼科疾病精准诊疗工程技术研究中心,上海200080

出　　处：《中华眼科杂志》2023年第9期757-763,共7页Chinese Journal of Ophthalmology

摘　　要：近视眼和青光眼是威胁视力的两大常见眼病,给患者家庭及社会造成了巨大的健康和经济负担。近年来,二者的关系问题逐渐成为研究热点。本文系统性综述了目前关于近视眼与青光眼关系的研究进展,主要论述了近视眼是青光眼发病的危险因素、近视眼对青光眼进展有多重影响两大观点,列举了可能的机制和潜在的临床标志物,并总结了学界对这两大观点的补充和质疑,提出了现有研究中的尚待解决的问题,以期在未来的科学探索中进一步阐明近视眼和青光眼的关系,优化青光眼的临床诊治。Myopia and glaucoma are two common ocular diseases that pose significant health and economic burdens to patients,their families,and society.In recent years,the relationship between these two conditions has become a prominent research focus.This article provides a systematic review of the current research progress on the association between myopia and glaucoma,with a primary emphasis on discussing the two major viewpoints:myopia as a risk factor for glaucoma development and the multifaceted impact of myopia on glaucoma progression.Possible mechanisms and potential clinical biomarkers are outlined,and the academic community′s complementary insights and doubts regarding these viewpoints are summarized.Additionally,unresolved issues in existing studies are identified to pave the way for future scientific explorations,aiming to further elucidate the relationship between myopia and glaucoma and optimize the clinical diagnosis and management of glaucoma.

关 键 词：近视 青光眼 危险因素 生物标记 

分 类 号：R778.11[医药卫生—眼科] R775[医药卫生—临床医学]